MICU intern's survival guide vasopressors: Difference between revisions

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** Its action is dose dependent. At low doses it predominantly acts on cardiac receptors (1-10 mcg/min) with less vasoconstriction activities. At higher doses it has both vasoconstriction and cardiac activities.
** Its action is dose dependent. At low doses it predominantly acts on cardiac receptors (1-10 mcg/min) with less vasoconstriction activities. At higher doses it has both vasoconstriction and cardiac activities.
* '''Indications:'''
* '''Indications:'''
** [[Cardiogenic shock]]
** [[Septic shock]]
** [[Septic shock]]
** [[Cardiogenic shock]] - Recent studies have shown that [[norepinephrine]] may be better than [[dopamine]] in [[cardiogenic shock]] due to a decreased risk of [[tachyarrhythmia]]s.
** In cases where the type of shock is unclear, [[norepinephrine]] can be tried as a first line agent.
** In cases where the type of shock is unclear, [[norepinephrine]] can be tried as a first line agent.
** Doses - 1-30 mcg/min.
** Doses - 1-30 mcg/min.

Revision as of 14:24, 28 December 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Norepinephrine

Dobutamine

Vasopressin

Dopamine

  • Mechanism of action
    • Acts on alpha1 (vasoconstriction of blood vessels), beta1 (increases cardiac output) and dopamine receptors (scattered throughout the body).
    • Its action is dose dependent. At low doses it predominantly acts on cardiac receptors (1-10 mcg/min) with less vasoconstriction activities. At higher doses it has both vasoconstriction and cardiac activities.
  • Indications:

Phenylephrine

References

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