List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and immunity disorders

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3. Endocrine, nutritional and metabolic diseases, and immunity disorders (240-279)

disorders of thyroid gland (240-246)

(240) Simple and unspecified goiter
- (240.9) Goiter, unspec.
(241) Nontoxic nodular goiter
- (241.0) Thyroid nodule
- (241.9) Goiter, unspec. nontoxic nodular
(242) Thyrotoxicosis with or without goiter
- (242.0) Goiter toxic, diffuse
- (242.9) Hyperthyroidism, NOS
(243) Congenital hypothyroidism
(244) Acquired hypothyroidism
(245) Thyroiditis
(246) Other disorders of thyroid
- (246.2) Thyroid cyst

diseases of other endocrine glands (250-259)

Note: for 250-259, the following fifth digit can be added:
- (250.x0) Diabetes mellitus type 2
- (250.x1) Diabetes mellitus type 1
- (250.x2) Diabetes mellitus type 2, uncontrolled
- (250.x3) Diabetes mellitus type 1, uncontrolled
(250) Diabetes mellitus
- (250.0) Diabetes mellitus without mention of complication
- (250.1) Diabetes with ketoacidosis
- (250.2) Diabetes with hyperosmolarity
- (250.3) Diabetes with other coma
- (250.4) Diabetes with renal manifestations
- (250.5) Diabetes with ophthalmic manifestations
- (250.6) Diabetes with neurological manifestations
- (250.7) Diabetes with peripheral circulatory disorders
- (250.8) Diabetes with other specified manifestations
- (250.9) Diabetes with unspecified complication
(251) Other disorders of pancreatic internal secretion
- (251.2) Hypoglycemia, nondiabetic, unspec.
(252) Disorders of parathyroid gland
- (252.0) Hyperparathyroidism, unspec.
  - (252.01) Hyperparathyroidism, primary
- (252.1) Hypoparathyroidism
(253) Disorders of the pituitary gland and its hypothalamic control
- (253.3) Growth hormone deficiency
- (253.6) SIADH
(254) Diseases of thymus gland
(255) Disorders of adrenal glands
- (255.0) Cushing's syndrome
(256) Ovarian dysfunction
- (256.2) Ovarian failure, postablative
  - (256.39) Ovarian failure, other
- (256.4) Ovaries, polycystic
(257) Testicular dysfunction
- (257.2) Testicular hypofunction
(258) Polyglandular dysfunction and related disorders
(259) Other endocrine disorders
- (259.0) Puberty, delayed
- (259.1) Sexual precocity

nutritional deficiencies (260-269)

(260) Kwashiorkor
(261) Nutritional marasmus
(262) Other severe protein-calorie malnutrition
(263) Other and unspecified protein-calorie malnutrition
(264) Vitamin A deficiency
- (264.0) With conjunctival xerosis
- (264.1) With conjunctival xerosis and Bitot's spot
- (264.2) With corneal xerosis
- (264.3) With corneal ulceration and xerosis
- (264.4) With keratomalacia
- (264.5) With night blindness
- (264.6) With xerophthalmic scars of cornea
- (264.7) Other ocular manifestations of vitamin A deficiency
- (264.8) Other manifestations of vitamin A deficiency
- (264.9) Unspecified vitamin A deficiency
(265) Thiamine and niacin deficiency states
- (265.0) Beriberi
- (265.1) Other and unspecified manifestations of thiamine deficiency
  - Wernicke's encephalopathy
- (265.2) Pellagra
(266) Deficiency of B-complex components
- (266.0) Ariboflavinosis
- (266.2) B12 deficiency w/o anemia
(267) Ascorbic acid deficiency
(268) Vitamin D deficiency
(269) Other nutritional deficiencies
- (269.0) Deficiency of vitamin K
- (269.1) Deficiency of other vitamins
- (269.2) Unspecified vitamin deficiency
- (269.3) Mineral deficiency, not elsewhere classified

other metabolic and immunity disorders (270-279)

(270) Disorders of amino-acid transport and metabolism
- (270.0) Disturbances of amino-acid transport
- (270.1) Phenylketonuria (PKU)
- (270.2) Other disturbances of aromatic amino-acid metabolism
- (270.3) Disturbances of branched-chain amino-acid metabolism
  - Maple syrup urine disease
- (270.4) Disturbances of sulphur-bearing amino-acid metabolism
  - Homocystinuria
- (270.6) Disorders of urea cycle metabolism
  - Citrullinemia
  - Hyperammonemia
- (270.8) Other specified disorders of amino-acid metabolism
  - Trimethylaminuria

(271) Disorders of carbohydrate transport and metabolism
- (271.0) Glycogenosis
- (271.1) Galactosemia
- (271.2) Hereditary fructose intolerance
- (271.3) Intestinal disaccharidase deficiencies and disaccharide malabsorption
  - Lactose intolerance
  - Glucose intolerance
- (271.4) Renal glycosuria
(272) Disorders of lipoid metabolism
- (272.0) Pure hypercholesterolemia
  - Fredrickson Type IIa hyperlipoproteinemia
  - Familial hypercholesterolemia
- (272.1) Pure hyperglyceridemia
  - Hypertriglyceridemia, essential
  - Fredrickson Type IV hyperlipoproteinemia
- (272.2) Hyperlipidemia, mixed
- (272.3) Hyperchylomicronemia
  - Bürger-Grütz syndrome
  - Fredrickson type I or V hyperlipoproteinemia
  - Hyperlipidemia, Group D
  - Mixed hyperglyceridemia
- (272.4) Other and unspecified hyperlipidemia
  - Alpha-lipoproteinemia
  - Combined hyperlipidemia
- (272.5) Lipoprotein deficiencies
  - Abetalipoproteinemia
  - Bassen-Kornzweig syndrome
  - High-density lipoid deficiency
  - Hypoalphalipoproteinemia
  - Hypobetalipoproteinemia (familial)
- (272.6) Lipodystrophy
- (272.7) Lipidoses
- (272.8) Other disorders of lipoid metabolism
  - Carnitine-acylcarnitine translocase deficiency
  - Mitochondrial trifunctional protein deficiency

(273) Disorders of plasma protein metabolism
- (273.0) Polyclonal hypergammaglobulinemia
- (273.1) Monoclonal paraproteinemia
- (273.2) Other paraproteinemias
- (273.3) Macroglobulinemia
  - Waldenström macroglobulinemia
- (273.8) Other disorders of plasma protein metabolism

(274) Gout
- (274.0) Gouty arthropathy
(275) Disorders of mineral metabolism
- (275.0) Disorders of iron metabolism
  - Hemochromatosis
- (275.1) Disorders of copper metabolism
  - Wilson's disease
- (275.2) Disorders of magnesium metabolism
  - Hypermagnesemia
  - Hypomagnesemia
- (275.3) Disorders of phosphorus metabolism
  - Familial hypophosphatemia
  - Hypophosphatasia
- (275.4) Disorders of calcium metabolism
  - (275.41) Hypocalcemia
  - (275.42) Hypercalcemia
  - (275.49) Pseudohypoparathyroidism
(276) Disorders of fluid, electrolyte, and acid-base balance
- (276.0) Hypernatremia
- (276.1) Hyponatremia
- (276.2) Acidosis
- (276.3) Alkalosis
- (276.4) Mixed acid-base balance disorder
- (276.5) Dehydration
  - (276.52) Hypovolemia
- (276.7) Hyperkalemia
- (276.8) Hypokalemia
(277) Other and unspecified disorders of metabolism
- (277.0) Cystic fibrosis
- (277.1) Disorders of porphyrin metabolism
  - Porphyria
    - Acute intermittent porphyria
- (277.2) Other disorders of purine and pyrimidine metabolism
  - Lesch-Nyhan syndrome
  - Xanthinuria
- (277.3) Amyloidosis
  - Familial Mediterranean fever
- (277.4) Hyperbilirubinemia
  - Crigler-Najjar syndrome
  - Gilbert's syndrome
- (277.5) Mucopolysaccharidosis
- (277.6) Other deficiencies of circulating enzymes
  - Alpha 1-antitrypsin deficiency
  - Hereditary angioedema
- (277.7) Dysmetabolic syndrome x
  - Metabolic syndrome
- (277.8) Other specified disorders of metabolism
  - (277.81) Primary carnitine deficiency
  - (277.82) Carnitine deficiency due to inborn errors of metabolism
  - (277.83) Iatrogenic carnitine deficiency
  - (277.84) Other secondary carnitine deficiency
  - (277.85) Disorders of fatty acid oxidation metabolism
  - (277.86) Disorders of peroxisomal metabolism
    - Zellweger syndrome
  - (277.87) Disorders of mitochondrial metabolism
    - Kearns-Sayre syndrome
    - Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome)
    - Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE)
    - Myoclonus with epilepsy and with ragged red fibers (MERRF syndrome)
    - Neuropathy, ataxia and retinitis pigmentosa (NARP syndrome)
  - (277.89) Other specified disorders of metabolism

(278) Obesity and other hyperalimentation
- (278.0) Obesity, NOS
- (278.1) Localized adiposity
- (278.2) Hypervitaminosis A
- (278.3) Hypercarotinemia
- (278.4) Hypervitaminosis D

(279) Disorders involving the immune mechanism
- (279.0) Deficiency of humoral immunity
- (279.1) Deficiency of cell-mediated immunity
  - (279.11) DiGeorge syndrome
  - (279.12) Wiskott-Aldrich syndrome
- (279.2) Combined immunity deficiency
  - Severe combined immunodeficiency

See also

v t e Endocrine pathology: endocrine diseases (E00-35, 240-259)
Thyroid	Hypothyroidism (Iodine deficiency, Cretinism, Congenital hypothyroidism, Goitre, Myxedema) - Hyperthyroidism (Graves disease, Toxic multinodular goitre, Teratoma with thyroid tissue or Struma ovarii) - Thyroiditis (De Quervain's thyroiditis, Hashimoto's thyroiditis, Riedel's thyroiditis) - Euthyroid sick syndrome
Pancreas	Diabetes mellitus (type 1, type 2, coma, angiopathy, ketoacidosis, nephropathy, neuropathy, retinopathy) - Hypoglycemia - Hyperinsulinism - Zollinger-Ellison syndrome - insulin receptor (Rabson-Mendenhall syndrome)
Parathyroid	Hypoparathyroidism (Pseudohypoparathyroidism) - Hyperparathyroidism (Primary, Secondary, Tertiary)
Pituitary	Hyperpituitarism (Acromegaly, Hyperprolactinaemia, SIADH) - Hypopituitarism (Simmonds' disease / Sheehan's syndrome, Kallmann syndrome, Growth hormone deficiency, Diabetes insipidus) - Adiposogenital dystrophy - Empty sella syndrome - Hypophysitis
Adrenal	Cushing's syndrome (Nelson's syndrome, Pseudo-Cushing's syndrome) - CAH (Lipoid, 3β, 11β, 17α, 21α) - Hyperaldosteronism (Conn syndrome, Bartter syndrome) - Adrenal insufficiency (Addison's disease) - Hypoaldosteronism
Gonads	Ovarian dysfunction (Polycystic ovary syndrome, Premature ovarian failure) - Testicular dysfunction (5-alpha-reductase deficiency) - Testosterone biosynthesis (17-beta-hydroxysteroid dehydrogenase deficiency) - General (Hypogonadism, Delayed puberty, Precocious puberty)
Other	Androgen insensitivity syndrome - Autoimmune polyendocrine syndrome - Carcinoid syndrome - Gigantism - Short stature (Laron syndrome, Psychogenic dwarfism) - Multiple endocrine neoplasia (1, 2) - Progeria - Woodhouse-Sakati syndrome

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