Lipoprotein disorders

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Lipoprotein disorders
ICD-10 E78
ICD-9 272
MeSH C18.452.339

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Dyslipidemia is a disruption in the amount of lipids in the blood.

In western societies, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia.

Classification

There are two major ways in which dyslipidemias are classified:

  • Phenotype, or the presentation in the body (including the specific type of lipid that is increased)
  • Etiology, or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify.

Types

Increases

These conditions are discussed in greater detail at hyperlipidemia.

Familial hypercholesterolemia is a specific form of hypercholesterolemia due to a defect on chromosome 19 (19p13.1-13.3).

Decreases

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