Lipoma Classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

There are many subtypes of lipomas:[1]

  • Adenolipomas are lipomas associated with eccrine sweat glands.[2]
  • Angiolipoleiomyomas are acquired, solitary, asymptomatic acral nodules, characterized histologically by well-circumscribed subcutaneous tumors composed of smooth muscle cells, blood vessels, connective tissue, and fat.
  • Angiolipomas painful subcutaneous nodules having all other features of a typical lipoma.[1]:624[3]
  • Cerebellar pontine angle and internal auditory canal lipomas[4]
  • Chondroid lipomas are deep-seated, firm, yellow tumors that characteristically occur on the legs of women.
  • Corpus callosum lipoma is a rare congenital brain condition that may or may not present with symptoms.[5] This occurs in the corpus callosum, also known as the colossal commissure, which is a wide, flat bundle of neural fibers beneath the cortex in the human brain.
  • Hibernomas are lipoma of brown fat.
  • Intradermal spindle cell lipomas are distinct in that they most commonly affect women and have a wide distribution, occurring with relatively equal frequency on the head and neck, trunk, and upper and lower extremities.[1]:625[3]
  • Neural fibrolipomas are overgrowths of fibro-fatty tissue along a nerve trunk, which often leads to nerve compression.
  • Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men and are characterized by floret giant cells with overlapping nuclei.
  • Spindle-cell lipomas are asymptomatic, slow-growing subcutaneous tumors that have a predilection for the posterior back, neck, and shoulders of older men.
  • Superficial subcutaneous lipomas, the most common type of lipoma, lie just below the surface of the skin. Most occur on the trunk, thigh, and forearm, although they may be found anywhere in the body where fat is located.

References

  1. 1.0 1.1 1.2 James, William D.; Berger, Timothy G.; Elston, Dirk M. (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). London: Elsevier. ISBN 0-7216-2921-0.
  2. James, William D.; Berger, Timothy G.; Elston, Dirk M. (2011). Andrews' Diseases of the Skin: Clinical Dermatology (11th ed.). London: Elsevier. ISBN 9781437703146.
  3. 3.0 3.1 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1838. ISBN 1-4160-2999-0.
  4. Crowson MG, Symons SP, Chen JM. "Left cerebellopontine angle lipoma with mild brainstem compression in a 13-year-old female". Otology& Neurotology.
  5. Wallace D (December 1976). "Lipoma of the corpus callosum". J Neurol Neurosurg Psychiatry. 39 (12): 1179–85. doi:10.1136/jnnp.39.12.1179. PMC 492562. PMID 1011028.