Leiomyosarcoma

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Leiomyosarcoma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Leiomyosarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Leiomyosarcoma from other Diseases

Epidemiology and Demographics

Risk Factors: Following Risk Fcators found to be associated with the development of the leiomyosarcoma

  • Age: Leiomyosarcoma can be seen at 20 years of age but mean age at diagnosis is 60 years old.
  • Race:Black women have a higher incidence of development of the leiomyosarcoma as compared to the white women.
  • Long term use of the tamoxifen: Prolonged use of the tamoxifen esp more than five years has been associated with the increased use of development of leiomyosarcoma
  • History of Pelvic radiations:Pelvic irradiation has been associated with the increased development of the leiomyosarcoma.

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

Uterine sarcoma


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