Laryngeal cancer risk factors: Difference between revisions
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==Overview== | |||
Common risk factors in the development of laryngeal cancer are smoking tobacco, chewing tobacco, and heavy alcohol consumption.<ref name=aaa>Hypopharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/types/head-and-neck/patient/hypopharyngeal-treatment-pdq Accessed on October 7, 2015.</ref> | |||
== | ==Risk Factors== | ||
Common risk factors for the development of laryngeal cancer include:<ref name=aaa>Hypopharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/types/head-and-neck/patient/hypopharyngeal-treatment-pdq Accessed on October 7, 2015</ref> | |||
*Smoking tobacco | |||
*Chewing tobacco | |||
*Heavy alcohol consumption | |||
*Diet without essential nutrients | |||
*[[HPV]] infection | |||
*Areca nut and betel quid chewing habit | |||
*Occupational exposures of substances such as: | |||
:*Organic solvents | |||
:*Coal dust | |||
:*Cement dust | |||
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Smoking | |||
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*Mutations may change a normal DNA sequence to an oncogene, which is a gene that causes cancer after exposure to a [[carcinogen]]. | |||
*Squamous cells, a type of cell that lines hollow organs like the throat, mouth, lungs, and outer layer of skin, are particularly vulnerable when exposed to cigarette smoke. | |||
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Heavy alcohol consumption | |||
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*Heavy alcohol consumption is linked to laryngeal cancer as well. Alcohol damages the lining of the larynx, increasing the amount of chemicals that are allowed to seep into the underlying membranes. Heavy alcohol use is also associated with nutritional deficiencies. | |||
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==Risk Factors== | ==Risk Factors== | ||
Smoking is the most important risk factor for laryngeal cancer. Heavy chronic consumption of [[alcohol]], particularly alcoholic spirits, is also significant. When combined, these two factors appear to have a synergistic effect. | Smoking is the most important risk factor for laryngeal cancer. Heavy chronic consumption of [[alcohol]], particularly alcoholic spirits, is also significant. When combined, these two factors appear to have a synergistic effect. | ||
Revision as of 18:53, 26 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Common risk factors in the development of laryngeal cancer are smoking tobacco, chewing tobacco, and heavy alcohol consumption.[1]
Risk Factors
Common risk factors for the development of laryngeal cancer include:[1]
- Smoking tobacco
- Chewing tobacco
- Heavy alcohol consumption
- Diet without essential nutrients
- HPV infection
- Areca nut and betel quid chewing habit
- Occupational exposures of substances such as:
- Organic solvents
- Coal dust
- Cement dust
| Risk Factors | Description |
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Smoking |
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Heavy alcohol consumption |
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Risk Factors
Smoking is the most important risk factor for laryngeal cancer. Heavy chronic consumption of alcohol, particularly alcoholic spirits, is also significant. When combined, these two factors appear to have a synergistic effect. Some other quoted risk factors are likely, in part, to be related to prolonged alcohol and tobacco consumption. These include low socioeconomic status, male sex, and age greater than 55 years.
People with a previous history of head and neck cancer are known to be at higher risk (about 25%) of developing a second cancer of the head, neck, or lung. This is mainly because in a significant proportion of these patients, the aerodigestive tract and lung epithelium have been exposed chronically to the carcinogenic effects to alcohol and tobacco. In this situation, a field change effect may occur, where the epithelial tissues start to become diffusely dysplastic with a reduced threshold for malignant change. This risk may be reduced by quitting alcohol and tobacco.
Known risk factors Possible risk factors
Smoking Alcohol Combined smoking and alcohol use Asbestos Sulphuric acid
Gastroesophageal reflux Family history of cancer Diet HPV
Read more: http://www.cancer.ca/en/cancer-information/cancer-type/laryngeal/risks/?region=on#ixzz3pDOKvWBw
References
- ↑ 1.0 1.1 Hypopharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/types/head-and-neck/patient/hypopharyngeal-treatment-pdq Accessed on October 7, 2015.