Laryngeal cancer risk factors: Difference between revisions
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People with a previous history of [[head and neck cancer]] are known to be at higher risk (about 25%) of developing a second cancer of the head, neck, or lung. This is mainly because in a significant proportion of these patients, the aerodigestive tract and lung epithelium have been exposed chronically to the carcinogenic effects to alcohol and [[tobacco]]. In this situation, a field change effect may occur, where the epithelial tissues start to become diffusely dysplastic with a reduced threshold for malignant change. This risk may be reduced by quitting alcohol and tobacco. | People with a previous history of [[head and neck cancer]] are known to be at higher risk (about 25%) of developing a second cancer of the head, neck, or lung. This is mainly because in a significant proportion of these patients, the aerodigestive tract and lung epithelium have been exposed chronically to the carcinogenic effects to alcohol and [[tobacco]]. In this situation, a field change effect may occur, where the epithelial tissues start to become diffusely dysplastic with a reduced threshold for malignant change. This risk may be reduced by quitting alcohol and tobacco. | ||
Known risk factors | |||
Possible risk factors | |||
Smoking | |||
Alcohol | |||
Combined smoking and alcohol use | |||
Asbestos | |||
Sulphuric acid | |||
Gastroesophageal reflux | |||
Family history of cancer | |||
Diet | |||
HPV | |||
Read more: http://www.cancer.ca/en/cancer-information/cancer-type/laryngeal/risks/?region=on#ixzz3pDOKvWBw | |||
==References== | ==References== | ||
Revision as of 15:03, 21 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Risk Factors
Smoking is the most important risk factor for laryngeal cancer. Heavy chronic consumption of alcohol, particularly alcoholic spirits, is also significant. When combined, these two factors appear to have a synergistic effect. Some other quoted risk factors are likely, in part, to be related to prolonged alcohol and tobacco consumption. These include low socioeconomic status, male sex, and age greater than 55 years.
People with a previous history of head and neck cancer are known to be at higher risk (about 25%) of developing a second cancer of the head, neck, or lung. This is mainly because in a significant proportion of these patients, the aerodigestive tract and lung epithelium have been exposed chronically to the carcinogenic effects to alcohol and tobacco. In this situation, a field change effect may occur, where the epithelial tissues start to become diffusely dysplastic with a reduced threshold for malignant change. This risk may be reduced by quitting alcohol and tobacco.
Known risk factors Possible risk factors
Smoking Alcohol Combined smoking and alcohol use Asbestos Sulphuric acid
Gastroesophageal reflux Family history of cancer Diet HPV
Read more: http://www.cancer.ca/en/cancer-information/cancer-type/laryngeal/risks/?region=on#ixzz3pDOKvWBw