Laryngeal cancer medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

The optimal therapy for laryngeal cancer depends on the stage at the time of diagnosis.

Medical Therapy

The medical therapy combined with radiation has largely replaced the surgical cure for laryngeal cancer depends on the stage at the time of diagnosis.[1] Multiple factors will be taken into account when considering treatment: [2][3]

Supportive Treatment

Many patients also need swallowing rehabilitation after treatment to help them adjust to the changes in the structure of the throat.

Radiation therapy

Radiotherapy may be of two types: External beam radiation therapy and internal radiation therapy.

  • External radiation therapy to the thyroid or the pituitary gland may alter thyroid gland functioning
  • Hyperfractionated radiation therapy and new types of radiation therapy are being studied in the treatment of laryngeal cancer

References

  1. Tamura Y, Tanaka S, Asato R, Hirano S, Yamashita M, Tamaki H, Ito J (February 2007). "Therapeutic outcomes of laryngeal cancer at Kyoto University Hospital for 10 years". Acta Otolaryngol Suppl (557): 62–5. doi:10.1080/00016480601067990. PMID 17453448.
  2. Lefebvre JL, Ang KK (April 2009). "Larynx preservation clinical trial design: key issues and recommendations-a consensus panel summary". Int. J. Radiat. Oncol. Biol. Phys. 73 (5): 1293–303. doi:10.1016/j.ijrobp.2008.10.047. PMID 19306746.
  3. Lefebvre JL, Ang KK (April 2009). "Larynx preservation clinical trial design: key issues and recommendations--a consensus panel summary". Head Neck. 31 (4): 429–41. doi:10.1002/hed.21081. PMID 19283793.


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