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==History and Symptoms==
==History and Symptoms==
There can be a patient history of the following
* [[Alcohol]]<ref name="pmid8704646">{{cite journal |vauthors=Andre K, Schraub S, Mercier M, Bontemps P |title=Role of alcohol and tobacco in the aetiology of head and neck cancer: a case-control study in the Doubs region of France |journal=Eur. J. Cancer, B, Oral Oncol. |volume=31B |issue=5 |pages=301–9 |date=September 1995 |pmid=8704646 |doi= |url=}}</ref><ref name="pmid9682771">{{cite journal |vauthors=De Stefani E, Boffetta P, Oreggia F, Fierro L, Mendilaharsu M |title=Hard liquor drinking is associated with higher risk of cancer of the oral cavity and pharynx than wine drinking. A case-control study in Uruguay |journal=Oral Oncol. |volume=34 |issue=2 |pages=99–104 |date=March 1998 |pmid=9682771 |doi= |url=}}</ref><ref name="pmid17505073">{{cite journal |vauthors=Hashibe M, Brennan P, Benhamou S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, Koifman S, La Vecchia C, Lazarus P, Levi F, Mates D, Matos E, Menezes A, Muscat J, Eluf-Neto J, Olshan AF, Rudnai P, Schwartz SM, Smith E, Sturgis EM, Szeszenia-Dabrowska N, Talamini R, Wei Q, Winn DM, Zaridze D, Zatonski W, Zhang ZF, Berthiller J, Boffetta P |title=Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium |journal=J. Natl. Cancer Inst. |volume=99 |issue=10 |pages=777–89 |date=May 2007 |pmid=17505073 |doi=10.1093/jnci/djk179 |url=}}</ref><ref name="pmid9529030">{{cite journal |vauthors=Lewin F, Norell SE, Johansson H, Gustavsson P, Wennerberg J, Biörklund A, Rutqvist LE |title=Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden |journal=Cancer |volume=82 |issue=7 |pages=1367–75 |date=April 1998 |pmid=9529030 |doi= |url=}}</ref>
* [[Alcohol]]<ref name="pmid8704646">{{cite journal |vauthors=Andre K, Schraub S, Mercier M, Bontemps P |title=Role of alcohol and tobacco in the aetiology of head and neck cancer: a case-control study in the Doubs region of France |journal=Eur. J. Cancer, B, Oral Oncol. |volume=31B |issue=5 |pages=301–9 |date=September 1995 |pmid=8704646 |doi= |url=}}</ref><ref name="pmid9682771">{{cite journal |vauthors=De Stefani E, Boffetta P, Oreggia F, Fierro L, Mendilaharsu M |title=Hard liquor drinking is associated with higher risk of cancer of the oral cavity and pharynx than wine drinking. A case-control study in Uruguay |journal=Oral Oncol. |volume=34 |issue=2 |pages=99–104 |date=March 1998 |pmid=9682771 |doi= |url=}}</ref><ref name="pmid17505073">{{cite journal |vauthors=Hashibe M, Brennan P, Benhamou S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, Koifman S, La Vecchia C, Lazarus P, Levi F, Mates D, Matos E, Menezes A, Muscat J, Eluf-Neto J, Olshan AF, Rudnai P, Schwartz SM, Smith E, Sturgis EM, Szeszenia-Dabrowska N, Talamini R, Wei Q, Winn DM, Zaridze D, Zatonski W, Zhang ZF, Berthiller J, Boffetta P |title=Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium |journal=J. Natl. Cancer Inst. |volume=99 |issue=10 |pages=777–89 |date=May 2007 |pmid=17505073 |doi=10.1093/jnci/djk179 |url=}}</ref><ref name="pmid9529030">{{cite journal |vauthors=Lewin F, Norell SE, Johansson H, Gustavsson P, Wennerberg J, Biörklund A, Rutqvist LE |title=Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden |journal=Cancer |volume=82 |issue=7 |pages=1367–75 |date=April 1998 |pmid=9529030 |doi= |url=}}</ref>
* [[Tobacco]] products<ref name="pmid8704646" /><ref name="pmid9529030" /><ref name="pmid8209260">{{cite journal |vauthors=Spitz MR |title=Epidemiology and risk factors for head and neck cancer |journal=Semin. Oncol. |volume=21 |issue=3 |pages=281–8 |date=June 1994 |pmid=8209260 |doi= |url=}}</ref><ref name="pmid3365707">{{cite journal |vauthors=Blot WJ, McLaughlin JK, Winn DM, Austin DF, Greenberg RS, Preston-Martin S, Bernstein L, Schoenberg JB, Stemhagen A, Fraumeni JF |title=Smoking and drinking in relation to oral and pharyngeal cancer |journal=Cancer Res. |volume=48 |issue=11 |pages=3282–7 |date=June 1988 |pmid=3365707 |doi= |url=}}</ref><ref name="pmid23817919">{{cite journal |vauthors=Wyss A, Hashibe M, Chuang SC, Lee YC, Zhang ZF, Yu GP, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Schantz S, Rudnai P, Purdue MP, Eluf-Neto J, Muscat J, Morgenstern H, Michaluart P, Menezes A, Matos E, Mates IN, Lissowska J, Levi F, Lazarus P, La Vecchia C, Koifman S, Herrero R, Hayes RB, Franceschi S, Wünsch-Filho V, Fernandez L, Fabianova E, Daudt AW, Dal Maso L, Curado MP, Chen C, Castellsague X, de Carvalho MB, Cadoni G, Boccia S, Brennan P, Boffetta P, Olshan AF |title=Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium |journal=Am. J. Epidemiol. |volume=178 |issue=5 |pages=679–90 |date=September 2013 |pmid=23817919 |pmc=3755640 |doi=10.1093/aje/kwt029 |url=}}</ref>
* [[Tobacco]] products<ref name="pmid8704646" /><ref name="pmid9529030" /><ref name="pmid8209260">{{cite journal |vauthors=Spitz MR |title=Epidemiology and risk factors for head and neck cancer |journal=Semin. Oncol. |volume=21 |issue=3 |pages=281–8 |date=June 1994 |pmid=8209260 |doi= |url=}}</ref><ref name="pmid3365707">{{cite journal |vauthors=Blot WJ, McLaughlin JK, Winn DM, Austin DF, Greenberg RS, Preston-Martin S, Bernstein L, Schoenberg JB, Stemhagen A, Fraumeni JF |title=Smoking and drinking in relation to oral and pharyngeal cancer |journal=Cancer Res. |volume=48 |issue=11 |pages=3282–7 |date=June 1988 |pmid=3365707 |doi= |url=}}</ref><ref name="pmid23817919">{{cite journal |vauthors=Wyss A, Hashibe M, Chuang SC, Lee YC, Zhang ZF, Yu GP, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Schantz S, Rudnai P, Purdue MP, Eluf-Neto J, Muscat J, Morgenstern H, Michaluart P, Menezes A, Matos E, Mates IN, Lissowska J, Levi F, Lazarus P, La Vecchia C, Koifman S, Herrero R, Hayes RB, Franceschi S, Wünsch-Filho V, Fernandez L, Fabianova E, Daudt AW, Dal Maso L, Curado MP, Chen C, Castellsague X, de Carvalho MB, Cadoni G, Boccia S, Brennan P, Boffetta P, Olshan AF |title=Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium |journal=Am. J. Epidemiol. |volume=178 |issue=5 |pages=679–90 |date=September 2013 |pmid=23817919 |pmc=3755640 |doi=10.1093/aje/kwt029 |url=}}</ref>

Revision as of 21:02, 10 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

The hallmark of laryngeal cancer is hoarseness. A positive history of neck lump and hoarseness is suggestive of laryngeal cancer. Common symptoms include lump in the neck, dysphagia, and hoarseness.

History and Symptoms

There can be a patient history of the following

Based on the locationn of the tumor, symptoms may differ but commonly include:[18][19]

Dysphagia Chronic cough Hemoptysis Dyspnea Otalgia

References

  1. ↑ 1.0 1.1 Andre K, Schraub S, Mercier M, Bontemps P (September 1995). "Role of alcohol and tobacco in the aetiology of head and neck cancer: a case-control study in the Doubs region of France". Eur. J. Cancer, B, Oral Oncol. 31B (5): 301–9. PMID 8704646.
  2. ↑ De Stefani E, Boffetta P, Oreggia F, Fierro L, Mendilaharsu M (March 1998). "Hard liquor drinking is associated with higher risk of cancer of the oral cavity and pharynx than wine drinking. A case-control study in Uruguay". Oral Oncol. 34 (2): 99–104. PMID 9682771.
  3. ↑ Hashibe M, Brennan P, Benhamou S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, Koifman S, La Vecchia C, Lazarus P, Levi F, Mates D, Matos E, Menezes A, Muscat J, Eluf-Neto J, Olshan AF, Rudnai P, Schwartz SM, Smith E, Sturgis EM, Szeszenia-Dabrowska N, Talamini R, Wei Q, Winn DM, Zaridze D, Zatonski W, Zhang ZF, Berthiller J, Boffetta P (May 2007). "Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium". J. Natl. Cancer Inst. 99 (10): 777–89. doi:10.1093/jnci/djk179. PMID 17505073.
  4. ↑ 4.0 4.1 Lewin F, Norell SE, Johansson H, Gustavsson P, Wennerberg J, Biörklund A, Rutqvist LE (April 1998). "Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden". Cancer. 82 (7): 1367–75. PMID 9529030.
  5. ↑ Spitz MR (June 1994). "Epidemiology and risk factors for head and neck cancer". Semin. Oncol. 21 (3): 281–8. PMID 8209260.
  6. ↑ Blot WJ, McLaughlin JK, Winn DM, Austin DF, Greenberg RS, Preston-Martin S, Bernstein L, Schoenberg JB, Stemhagen A, Fraumeni JF (June 1988). "Smoking and drinking in relation to oral and pharyngeal cancer". Cancer Res. 48 (11): 3282–7. PMID 3365707.
  7. ↑ Wyss A, Hashibe M, Chuang SC, Lee YC, Zhang ZF, Yu GP, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Schantz S, Rudnai P, Purdue MP, Eluf-Neto J, Muscat J, Morgenstern H, Michaluart P, Menezes A, Matos E, Mates IN, Lissowska J, Levi F, Lazarus P, La Vecchia C, Koifman S, Herrero R, Hayes RB, Franceschi S, Wünsch-Filho V, Fernandez L, Fabianova E, Daudt AW, Dal Maso L, Curado MP, Chen C, Castellsague X, de Carvalho MB, Cadoni G, Boccia S, Brennan P, Boffetta P, Olshan AF (September 2013). "Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium". Am. J. Epidemiol. 178 (5): 679–90. doi:10.1093/aje/kwt029. PMC 3755640. PMID 23817919.
  8. ↑ Kobayashi I, Shima K, Saito I, Kiyoshima T, Matsuo K, Ozeki S, Ohishi M, Sakai H (September 1999). "Prevalence of Epstein-Barr virus in oral squamous cell carcinoma". J. Pathol. 189 (1): 34–9. doi:10.1002/(SICI)1096-9896(199909)189:1<34::AID-PATH391>3.0.CO;2-4. PMID 10451485.
  9. ↑ Mahale P, Sturgis EM, Tweardy DJ, Ariza-Heredia EJ, Torres HA (August 2016). "Association Between Hepatitis C Virus and Head and Neck Cancers". J. Natl. Cancer Inst. 108 (8). doi:10.1093/jnci/djw035. PMC 5017939. PMID 27075854.
  10. ↑ Das CM, Schantz SP, Shillitoe EJ (May 1993). "Antibody to a mutagenic peptide of herpes simplex virus in young adult patients with cancer of the head and neck". Oral Surg. Oral Med. Oral Pathol. 75 (5): 610–4. PMID 8387664.
  11. ↑ Rabinovics N, Mizrachi A, Hadar T, Ad-El D, Feinmesser R, Guttman D, Shpitzer T, Bachar G (February 2014). "Cancer of the head and neck region in solid organ transplant recipients". Head Neck. 36 (2): 181–6. doi:10.1002/hed.23283. PMID 23554129.
  12. ↑ Guha N, Warnakulasuriya S, Vlaanderen J, Straif K (September 2014). "Betel quid chewing and the risk of oral and oropharyngeal cancers: a meta-analysis with implications for cancer control". Int. J. Cancer. 135 (6): 1433–43. doi:10.1002/ijc.28643. PMID 24302487.
  13. ↑ Olsen J, Sabroe S (June 1984). "Occupational causes of laryngeal cancer". J Epidemiol Community Health. 38 (2): 117–21. PMID 6747509.
  14. ↑ Battista G, Belli S, Comba P, Fiumalbi C, Grignoli M, Loi F, Orsi D, Paredes I (November 1999). "Mortality due to asbestos-related causes among railway carriage construction and repair workers". Occup Med (Lond). 49 (8): 536–9. PMID 10658307.
  15. ↑ Roh S, Park S, Tae G, Song J (2016). "A case of laryngeal cancer induced by exposure to asbestos in a construction site supervisor". Ann Occup Environ Med. 28: 34. doi:10.1186/s40557-016-0114-3. PMC 4976513. PMID 27504188.
  16. ↑ Vaughan TL, Stewart PA, Davis S, Thomas DB (September 1997). "Work in dry cleaning and the incidence of cancer of the oral cavity, larynx, and oesophagus". Occup Environ Med. 54 (9): 692–5. PMC 1128846. PMID 9423585.
  17. ↑ Boffetta P, Hayes RB, Sartori S, Lee YC, Muscat J, Olshan A, Winn DM, Castellsagué X, Zhang ZF, Morgenstern H, Chen C, Schwartz SM, Vaughan TL, Wunsch-Filho V, Purdue M, Koifman S, Curado MP, Vilensky M, Gillison M, Fernandez L, Menezes A, Daudt AW, Schantz S, Yu G, D'Souza G, Haddad RI, La Vecchia C, Hashibe M (July 2016). "Mouthwash use and cancer of the head and neck: a pooled analysis from the International Head and Neck Cancer Epidemiology Consortium". Eur. J. Cancer Prev. 25 (4): 344–8. doi:10.1097/CEJ.0000000000000179. PMC 4752930. PMID 26275006.
  18. ↑ Jones TM, De M, Foran B, Harrington K, Mortimore S (May 2016). "Laryngeal cancer: United Kingdom National Multidisciplinary guidelines". J Laryngol Otol. 130 (S2): S75–S82. doi:10.1017/S0022215116000487. PMC 4873912. PMID 27841116.
  19. ↑ Jovanović MB (2008). "[Diagnosis of laryngeal carcinoma]". Med. Pregl. 61 (11–12): 591–5. PMID 19368278.


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