Intracerebral metastases surgery: Difference between revisions

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===Stereotactic Radiosurgery===
===Stereotactic Radiosurgery===
*Stereotactic radiosurgery is a type of external beam radiation therapy that allows radiation beams to be given to a specific area in the brain.  
*Stereotactic radiosurgery (SRS) delivers a single high dose of irradiation to the target volume while avoiding the surrounding normal tissues.<ref name="OwenSouhami2014">{{cite journal|last1=Owen|first1=Scott|last2=Souhami|first2=Luis|title=The Management of Brain Metastases in Non-Small Cell Lung Cancer|journal=Frontiers in Oncology|volume=4|year=2014|issn=2234-943X|doi=10.3389/fonc.2014.00248}}</ref>
*This therapy aims many small beams of radiation from different directions at the tissue to be treated.  
*This therapy aims small beams of radiation from different directions at the tissue to be treated.  
*It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
*It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
*A single large dose of radiation is given.
*A single large dose of radiation is given.

Revision as of 18:53, 16 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Surgery is not the first-line treatment option for patients with intracerebral metastases. Surgical resection is usually reserved for patients with either a solitary brain metastasis or no extracranial spread of the primary tumor. Sterotactic radiosurgery is indicated if there are multiple (<3) but small metastatic tumor masses.[1]

Surgery

Surgical Resection

Surgery is not the first-line treatment option for patients with intracerebral metastases. Surgical resection is usually reserved for patients with either:[1]

  • Solitary brain metastasis
  • No extracranial spread of the primary

The role of surgery in treatment of intracerebral metastases include:[1]

  • Reduction of the size of the tumor as much as possible (debulking), if the metastasis is deep or is growing into the brain tissue and causing problems
  • Reduction of the intracranial pressure
  • Relief from the symptoms, if a brain metastasis cannot be completely resected

Stereotactic Radiosurgery

  • Stereotactic radiosurgery (SRS) delivers a single high dose of irradiation to the target volume while avoiding the surrounding normal tissues.[2]
  • This therapy aims small beams of radiation from different directions at the tissue to be treated.
  • It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
  • A single large dose of radiation is given.
  • Indications for stereotactic radiation therapy include:[3]
  • One or a few metastatic brain tumors
  • Used to treat people with upto 3 small-sized metastatic brain tumors
  • Alone or in combination with whole brain radiation therapy (WBRT)
  • Progressive or recurrent brain metastases
  • Stereotactic radiotherapy may be given after the person has had whole brain radiation therapy

References

  1. 1.0 1.1 1.2 Surgery of brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015
  2. Owen, Scott; Souhami, Luis (2014). "The Management of Brain Metastases in Non-Small Cell Lung Cancer". Frontiers in Oncology. 4. doi:10.3389/fonc.2014.00248. ISSN 2234-943X.
  3. Sterotactic radiation therapy for brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015


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