Intracerebral metastases surgery: Difference between revisions

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==Overview==
==Overview==
[[Surgery]] is not the first-line treatment option for patients with intracerebral metastases. Surgical resection is usually reserved for patients with either a solitary brain metastasis or no extracranial spread of the primary tumor.<ref name=surgeryofbrainmets1>Surgery of brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015</ref>


==Surgery==
==Surgery==
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*This therapy aims many small beams of radiation from different directions at the tissue to be treated.  
*This therapy aims many small beams of radiation from different directions at the tissue to be treated.  
*It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
*It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
*A single large dose of radiation is given.
*A single large dose of radiation is given.
*Indications for stereotactic radiation therapy include:<ref name=sterotacticbrainmets1>Sterotactic radiation therapy for brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015</ref>
*Indications for stereotactic radiation therapy include:<ref name=sterotacticbrainmets1>Sterotactic radiation therapy for brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015</ref>
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*Solitary brain metastasis
*Solitary brain metastasis
*No extracranial spread of the primary
*No extracranial spread of the primary
*The role of surgery in treatment of intracerebral metastases include:<ref name=surgeryofbrainmets1>Surgery of brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015</ref>
 
:*Reduction of the size of the tumor as much as possible (''debulking''), if the metastasis is deep or is growing into the brain tissue and causing problems
The role of surgery in treatment of intracerebral metastases include:<ref name=surgeryofbrainmets1>Surgery of brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015</ref>
:*Reduction of the intracranial pressure
*Reduction of the size of the tumor as much as possible (''debulking''), if the metastasis is deep or is growing into the brain tissue and causing problems
:*Relief from the symptoms, if a brain metastasis cannot be completely resected
*Reduction of the intracranial pressure
*Relief from the symptoms, if a brain metastasis cannot be completely resected


==References==
==References==

Revision as of 23:57, 13 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Surgery is not the first-line treatment option for patients with intracerebral metastases. Surgical resection is usually reserved for patients with either a solitary brain metastasis or no extracranial spread of the primary tumor.[1]

Surgery

Stereotactic Radiosurgery

  • Stereotactic radiosurgery is a type of external beam radiation therapy that allows radiation beams to be given to a specific area in the brain.
  • This therapy aims many small beams of radiation from different directions at the tissue to be treated.
  • It can direct the beams with precision to lessen the radiation to surrounding tissues, hence it causes less damage to healthy tissue than whole brain radiation therapy.
  • A single large dose of radiation is given.
  • Indications for stereotactic radiation therapy include:[2]
  • One or a few metastatic brain tumors
  • Stereotactic radiosurgery is usually used to treat people with upto 3 metastatic brain tumors, although this depends on the size and location of the tumors. Occasionally, selected cases with more than 3 tumors may be treated if the tumors aren’t too big. Stereotactic radiosurgery may not be suitable for people with large metastatic brain tumors.
  • Alone or in combination with whole brain radiation therapy (WBRT)
  • Progressive or recurrent brain metastases
  • Stereotactic radiotherapy may be given after the person has had whole brain radiation therapy

Surgical Resection

Surgery is not the first-line treatment option for patients with intracerebral metastases. Surgical resection is usually reserved for patients with either:[1]

  • Solitary brain metastasis
  • No extracranial spread of the primary

The role of surgery in treatment of intracerebral metastases include:[1]

  • Reduction of the size of the tumor as much as possible (debulking), if the metastasis is deep or is growing into the brain tissue and causing problems
  • Reduction of the intracranial pressure
  • Relief from the symptoms, if a brain metastasis cannot be completely resected

References

  1. 1.0 1.1 1.2 Surgery of brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015
  2. Sterotactic radiation therapy for brain metastases. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/metastatic-cancer/brain-metastases/treatment/?region=on. Accessed on November 13, 2015


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