Interstitial nephritis: Difference between revisions

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'''''Synonyms and keywords:''''' Tubulo-interstitial nephritis
'''''Synonyms and keywords:''''' Tubulo-interstitial nephritis
==[[Interstitial nephritis overview|Overview]]==
==[[Interstitial nephritis overview|Overview]]==
Two main diseases involve the renal tubules are: Acute tubular necrosis due to Ischemic or toxic injury


==[[Interstitial nephritis historical perspective|Historical Perspective]]==
for more about ATN click here


==[[Interstitial nephritis classification|Classification]]==
and tubulointerstitial nephritis with Inflammatory involvement of tubules and interstitium and its consequent  reactions.
Tubulointerstitial nephritis (TIN) refers to a group of inflammatory diseases of the kidneys that primarily involve


the interstitium and tubules.The glomeruli may be spared altogether or affected only late in the course. In most cases
since The majority  cases of TIN are due  to bacterial infection, and the renal pelvis is deeply involved, therefore pyelonephritis is term describes this condition. And In general  


of TIN caused by bacterial infection, the renal pelvis is prominently involved—hence the more descriptive term
,The term interstitial nephritis is used for TIN that are owing to  '''nonbacterial causes''' of tubular injury such as  drugs, viral infections  autoimmune '''systemic diseases.'''


pyelonephritis (from pyelo, “pelvis”). The term interstitial nephritis generally is reserved for cases of TIN that are nonbacterial in origin. These include tubular injury resulting from drugs, metabolic disorders such as hypokalemia,
==[[Interstitial nephritis historical perspective|Historical Perspective]]==


physical injury such as irradiation, viral infections, and immune reactions. On the basis of clinical features and the
==[[Interstitial nephritis classification|Classification]]==
 
character of the inflammatory exudate, TIN, regardless of the etiologic agent, can be divided into acute and chronic


categories. Discussed next is acute pyelonephritis, which is always of bacterial origin, followed by consideration of
Tubulointerstitial nephritis (TIN) commonly attributes to inflammatory diseases of the kidneys with involvement the interstitium and tubules.  In this condition the glomeruli are intact or may affect in the late stage of disease. 


other, nonbacterial forms of interstitial nephritis.
 according to clinical manifestations and the  inflammatory process, TIN, in spite of the etiologic agent, can be divided into acute and chronic categories.


==[[Interstitial nephritis pathophysiology|Pathophysiology]]==
==[[Interstitial nephritis pathophysiology|Pathophysiology]]==

Revision as of 04:25, 27 June 2018


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Synonyms and keywords: Tubulo-interstitial nephritis

Overview

Two main diseases involve the renal tubules are: Acute tubular necrosis due to Ischemic or toxic injury

for more about ATN click here

and tubulointerstitial nephritis with Inflammatory involvement of tubules and interstitium and its consequent reactions.

since The majority  cases of TIN are due  to bacterial infection, and the renal pelvis is deeply involved, therefore pyelonephritis is term describes this condition. And In general  

,The term interstitial nephritis is used for TIN that are owing to  nonbacterial causes of tubular injury such as  drugs, viral infections  autoimmune systemic diseases.

Historical Perspective

Classification

Tubulointerstitial nephritis (TIN) commonly attributes to inflammatory diseases of the kidneys with involvement the interstitium and tubules.  In this condition the glomeruli are intact or may affect in the late stage of disease. 

 according to clinical manifestations and the  inflammatory process, TIN, in spite of the etiologic agent, can be divided into acute and chronic categories.

Pathophysiology

Causes

Differentiating Interstitial nephritis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | KUB X Ray | CT | MRI | Biopsy and Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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