Hyponatremia resident survival guide: Difference between revisions

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{{familytree | G01 | | G02 | | G03 | | G04 | | | | | | | | G01= GI, renal losses, <br> dehydration, diuretics, <br> adrenal insufficiency, <br> cerebral salt wasting <br> syndrome  | G02= heart failure <br> cirrhosis <br> renal failure | G03= Urine osmolality > 300 | G04= Urine osmolality 50-100}}
{{familytree | G01 | | G02 | | G03 | | G04 | | | | | | | | G01= GI, renal losses, <br> dehydration, diuretics, <br> adrenal insufficiency, <br> cerebral salt wasting <br> syndrome  | G02= heart failure <br> cirrhosis <br> renal failure | G03= Urine osmolality > 300 | G04= Urine osmolality 50-100}}
{{familytree | |!| | | |!| | | |!| | | |!| | | | | | | | | }}
{{familytree | |!| | | |!| | | |!| | | |!| | | | | | | | | }}
{{familytree | H01 | | H02 | | H03 | | H04 | | | | | | | | H01= (a) Normal saline; <br> (b) If neurological <br> sign/symptoms 3% <br> hypertonic saline, <br> and furosemide| H02=  Fluid restriction <br> Diuretics  <br> Treat etiology | H03= SIADH, Hypothyroidism | H04= Compulsive water drinking }}
{{familytree | H01 | | H02 | | H03 | | H04 | | | | | | | | H01= (a) Normal saline; <br> (b) If neurological <br> sign/symptoms 3% <br> hypertonic saline, <br> and furosemide| H02=  Fluid restriction, <br> Diuretics, <br> Treat etiology | H03= SIADH, Hypothyroidism | H04= Compulsive water drinking }}
{{familytree | | | | | | | | | |!| | | |!| | | | | | | | | }}
{{familytree | | | | | | | | | |!| | | |!| | | | | | | | | }}
{{familytree | | | | | | | | | I01 | | I02 | | | | | | | | I01= (a) Fluid restriction <br> (b) Demeclocycline (if  <br> fluid restriction fails) <br> (c) Vaptans; Conivaptan, <br> Tolvaptan for resistant cases  | I02= Treat etiology}}
{{familytree | | | | | | | | | I01 | | I02 | | | | | | | | I01= (a) Fluid restriction <br> (b) Demeclocycline (if  <br> fluid restriction fails) <br> (c) Vaptans; Conivaptan, <br> Tolvaptan for resistant cases  | I02= Treat etiology}}

Revision as of 19:55, 20 November 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Definition

Causes

Life Threatening Causes

Conditions that may cause death or permanent disability within the next 24 hours

Common Causes

Management

 
 
 
 
 
 
 
 
 
 
Serum sodium < 135 mEq/L
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Plasma osmolality
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hypotonic < 280
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Isotonic/Hypertonic
(Pseudohyponatremia) > 280
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Assess volume status
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Increase in osmotically active
compounds; glucose, protein, lipid,
mannitol, sorbitol
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hypovolemia
 
Hypervolemia
 
 
 
Euvolemia
 
 
 
 
 
 
 
Treat etiology
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Spot urine Na < 10,
BUN/Creatinine > 20:1,
Urine osmolality > 450
 
Same as hypovolemia,
Spot urine Na < 10,
BUN/Creatinine > 20:1,
Urine osmolality > 450
 
 
 
Spot urine Na > 20,
BUN/Creatinine < 20:1,
Urine osmolality > 300
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
GI, renal losses,
dehydration, diuretics,
adrenal insufficiency,
cerebral salt wasting
syndrome
 
heart failure
cirrhosis
renal failure
 
Urine osmolality > 300
 
Urine osmolality 50-100
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(a) Normal saline;
(b) If neurological
sign/symptoms 3%
hypertonic saline,
and furosemide
 
Fluid restriction,
Diuretics,
Treat etiology
 
SIADH, Hypothyroidism
 
Compulsive water drinking
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(a) Fluid restriction
(b) Demeclocycline (if
fluid restriction fails)
(c) Vaptans; Conivaptan,
Tolvaptan for resistant cases
 
Treat etiology
 
 
 
 
 
 
 

Do's

Don'ts

References


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