Hyperthyroidism medical therapy: Difference between revisions
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==Medical therapy== | ==Medical therapy== | ||
====Thyrostatics==== | ====Thyrostatics==== | ||
Thyrostatics are drugs that inhibit the production of thyroid hormones, such as [[carbimazole]] (used in UK) and [[methimazole]](used in US), or where these not tolerated then [[propylthiouracil]]. Thyrostatics are believed to work by inhibiting the iodination of thyroglobulin by thyroperoxidase. | Thyrostatics are drugs that inhibit the production of thyroid hormones, such as [[carbimazole]] (used in UK) and [[methimazole]] (used in US), or where these not tolerated then [[propylthiouracil]]. Thyrostatics are believed to work by inhibiting the iodination of thyroglobulin by thyroperoxidase. | ||
If too high a dose is used in pharmacological treatment, patients can develop symptoms of [[hypothyroidism]]. | If too high a dose is used in pharmacological treatment, patients can develop symptoms of [[hypothyroidism]]. | ||
Revision as of 14:15, 28 August 2012
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Hyperthyroidism Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The major and generally accepted modalities for treatment of hyperthyroidism in humans involve initial temporary use of suppressive thyrostatics medication, and possibly later use of permanent surgical or radioisotope therapy. All approaches may cause under active thyroid function (hypothyroidism) which is easily managed with levothyroxine supplementation.
Medical therapy
Thyrostatics
Thyrostatics are drugs that inhibit the production of thyroid hormones, such as carbimazole (used in UK) and methimazole (used in US), or where these not tolerated then propylthiouracil. Thyrostatics are believed to work by inhibiting the iodination of thyroglobulin by thyroperoxidase.
If too high a dose is used in pharmacological treatment, patients can develop symptoms of hypothyroidism.
Beta-blockers
Beta-blockers do not treat, but rather mask, common symptoms of hyperthyroidism such as palpitations, trembling, and anxiety. Propranolol in the UK, and Metoprolol in the US, are most frequently used to augment treatment for hyperthyroid patients.