Hyperlipoproteinemia laboratory findings

Jump to navigation Jump to search

Lipoprotein Disorders Microchapters

Patient Information

Overview

Causes

Classification

Hyperlipoproteinemia
Hypolipoproteinemia

Treatment

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

Complete lipid profile

The US National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) suggests screening asymptomatic individuals with a complete fasting lipid profile every 5 years. Obtain complete lipid profile after 9 to 12-hour fast. The reference values for making the diagnosis and risk stratification are depicted below:

Levels of total cholesterol (mg/dl)
<200 Desirable
200-239 Borderline high
≥240 High
Levels of LDL cholesterol (mg/dl)
<100 Optimal
100-129 Near optimal
130-159 Borderline high
160-189 High
≥190 Very high
Levels of HDL Cholesterol (mg/dl)
<40 Low
≥60 High
Levels of serum triglycerides (mg/dl)
<150 Normal
150-199 Borderline high
200-499 High
≥500 Very high

Other laboratory tests

For careful medical evaluation, must take into consideration all medications (both prescription and over-the-counter medications) and perform following tests to rule out secondary hyperlipidemias:

  • Serum thyroid-stimulating hormone
  • Liver function tests
  • Serum creatinine
  • Urinalysis

Other tests that may be done include: Studies of cells called fibroblasts to see how the body absorbs LDL cholesterol Gene or receptor analysis for the defect associated with this condition

References