Hemoglobinopathy: Difference between revisions
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==Classification== | ==Classification== | ||
Hemoglobinopathy be classified according to genetic and structure of hemoglobin into two main groups: | Hemoglobinopathy be classified according to genetic and structure of hemoglobin into two main groups:<ref name="pmid21886666">{{cite journal |vauthors=Kohne E |title=Hemoglobinopathies: clinical manifestations, diagnosis, and treatment |journal=Dtsch Arztebl Int |volume=108 |issue=31-32 |pages=532–40 |date=August 2011 |pmid=21886666 |pmc=3163784 |doi=10.3238/arztebl.2011.0532 |url=}}</ref> | ||
* Thalassemia syndromes | * Thalassemia syndromes | ||
**α-thalassemia | **α-thalassemia |
Revision as of 20:05, 30 August 2018
Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Hemoglobinopathy is a kind of genetic defect that results in abnormal structure of one of the globin chains of the hemoglobin molecule. Most common hemoglobinopathies include sickle-cell disease.
Classification
Hemoglobinopathy be classified according to genetic and structure of hemoglobin into two main groups:[1]
- Thalassemia syndromes
- α-thalassemia
- β-thalassemia
- Structural hemoglobin variants
- HbS
- HbE
- HbC
Common Causes
Common causes of [disease name] may include:
- [Cause1]
- [Cause2]
- [Cause3]
OR
- [Disease name] is caused by an infection with [pathogen name].
- [Pathogen name] is caused by [pathogen name].
Less Common Causes
Less common causes of [disease name] include:
- [Cause1]
- [Cause2]
- [Cause3]
Migration patterns
Common variants
- Hb S
- Hb C
- Hb E
- Hb D-Punjab
- Hb O-Arab
- Hb G-Philadelphia
- Hb Hasharon
- Hb Korle-Bu
- Hb Lepore
- Hb M
Hemoglobinopathy and evolution
de:Hämoglobinopathie nl:Hemoglobinopathie
- ↑ Kohne E (August 2011). "Hemoglobinopathies: clinical manifestations, diagnosis, and treatment". Dtsch Arztebl Int. 108 (31–32): 532–40. doi:10.3238/arztebl.2011.0532. PMC 3163784. PMID 21886666.