Helicobacter pylori infection differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Helicobacter pylori infection must be differentiated from other diseases that cause nausea, vomiting, abdominal pain, epigastric pain and unexplained weight loss such as atrophic gastritis, GERD, gastrinoma, peptic ulcer disease, gastric adenocarcinoma, stress-induced gastritis and Non-Hodgkin's lymphoma.

Differential Diagnosis

H.pylori infection must be differentiated from:

Disease	Cause	Symptoms							Diagnosis
		Pain			Nausea & Vomiting	Heartburn	Weight loss	Loss of Appetite	Endoscopy findings
		Location	Aggravating Factors	Alleviating Factors
Acute gastritis	H.pylori NSAIDS Corticosteroids Alcohol Spicy food Viral infections Crohn's disease Autoimmune diseases Bile reflux Cocaine use Breathing machine or ventilator Ingestion of corrosives
Chronic gastritis
Atrophic gastritis
Stress-induced gastritis	Surgery Systemic stress
GERD
Peptic ulcer disease
Gastrinoma
Gastric Adenocarcinoma
Non-Hodgkin's lymphoma