Headache differential diagnosis: Difference between revisions

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|History of relapses and remissions
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|'''↑'''  CSF IgG levels
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(monoclonal bands)
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|MRI
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|[[Hemorrhagic stroke]]
|[[Hemorrhagic stroke]]
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|HTN
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|<nowiki>+</nowiki>
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|CT scan  without contrast<ref name="pmid21694755">{{cite journal| author=Birenbaum D, Bancroft LW, Felsberg GJ| title=Imaging in acute stroke. | journal=West J Emerg Med | year= 2011 | volume= 12 | issue= 1 | pages= 67-76 | pmid=21694755 | doi= | pmc=3088377 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21694755  }}</ref><ref name="pmid21807345">{{cite journal| author=DeLaPaz RL, Wippold FJ, Cornelius RS, Amin-Hanjani S, Angtuaco EJ, Broderick DF et al.| title=ACR Appropriateness Criteria® on cerebrovascular disease. | journal=J Am Coll Radiol | year= 2011 | volume= 8 | issue= 8 | pages= 532-8 | pmid=21807345 | doi=10.1016/j.jacr.2011.05.010 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21807345  }}</ref>
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|[[Neurosyphilis]]
|[[Neurosyphilis]]
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|[[Sexually transmitted disease|STI]]<nowiki/>s
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|'''↑''' [[Leukocytes]] and [[protein]]
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|<nowiki>+</nowiki>
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|CSF [[VDRL]]-specifc
 
CSF FTA-Ab -sensitive<ref name="pmid22421697">{{cite journal| author=Ho EL, Marra CM| title=Treponemal tests for neurosyphilis--less accurate than what we thought? | journal=Sex Transm Dis | year= 2012 | volume= 39 | issue= 4 | pages= 298-9 | pmid=22421697 | doi=10.1097/OLQ.0b013e31824ee574 | pmc=3746559 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22421697  }}</ref>
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|[[Wernicke's encephalopathy|Wernicke’s encephalopathy]]
|[[Wernicke's encephalopathy|Wernicke’s encephalopathy]]
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|History of alcohal abuse
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|blood ethanol levels
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|<nowiki>+/-</nowiki>
|Clinical assesment and lab findings
|Clinical assesment and lab findings
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|Medication hx
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|Drug levels
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|Drug screen test
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|Metabolic disturbances  
|Metabolic disturbances  
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|Underlying CKD, CLD
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|[[Hypoglycemia]], [[Hyponatremia|hypo]] and [[hypernatremia]], [[Hypokalemia|hypo]] and [[hyperkalemia]]
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|Cause dependent
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|NPH
|NPH
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|OCP use, meds
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|CT  and clinical
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|Sinusitis
|Sinusitis
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|allergies, seasonal
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|CT
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Revision as of 06:10, 11 June 2020

Headache Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabeeh Islam, MBBS[2]


Disease History and Physical Examination PMHx Diagnostic approach
Unilateral Bilateral Throbbing character Autonomic symptoms Fever Photophobia Aphasia LOC Aura Nause/vomiting Rash Neck stiffness Vision changes Facial tenderness Neurologic deficits Labs and CSF findings CT/MRI Gold standard test
Migraine + - + - - + - - + + - - + - - Trigger factors, family hx - - Clinical assesment
Tension-type headache (TTH) - + - - - - - - - - - - - - - stress, genetics - - Clinical assesment
Cluster headache + - - + - - - - - - - - + - - episodic history - - Clinical assesment
Seizure - + - - - - +/- + +/- - - - - - +/- Hx of seizures prolactin level +/- mass lesion EEG
Meningitis - + - - + +/- +/- - - +/- +/- + - - + Hx of fever, malaise <math>\uparrow</math>WBC

<math>\uparrow</math>Protein

<math>\downarrow</math>glucose

+/- CSF analysis
Encephalitis - + +/- - + +/- +/- - - - +/- + - - + Hx of fever, malaise elevated WBC, low glucose + CSF PCR
Brain tumor - + - - - - +/- - - +/- - - +/- - +/- weight loss, fatigue neuromarkers +/- mass MRI
Subdural hemorrhage -/+ -/+ +/- - - - +/- - - - - - +/- - +/- Trauma, fall Xanthochromia + CT w/o contrast
Subarachnoid hemorrhage -/+ + +/- - - +/- +/- - - - - +/- +/- - +/- thunderclap headache <math>\uparrow</math>opening pressure, xanthochromia + CT w/o contrast
Hypertensive encephalopathy - + +/- - - +/- - - - - - - +/- - - Hypertension UA +/- +/- clinical assessment
CNS abscess -/+ -/+ - - + - +/- - - +/- +/- +/- +/- - +/- History of drug abuse, endocarditis, immunosupression leukocytes, glucose and protien + MRI
Conversion disorder -/+ -/+ - - - - +/- - - - - +/- +/- - +/- History of emotional stress - - Diagnosis of exclusion
Multiple sclerosis -/+ -/+ - - - - - - - - - - + - +/- History of relapses and remissions CSF IgG levels

(monoclonal bands)

+ MRI
Hemorrhagic stroke -/+ -/+ +/- - - - +/- - - - - - +/- - +/- HTN - + CT scan without contrast[1][2]
Neurosyphilis -/+ -/+ - - - - - +/- - - +/- - +/- - +/- STIs Leukocytes and protein + CSF VDRL-specifc

CSF FTA-Ab -sensitive[3]

Wernicke’s encephalopathy - -/+ - - - - +/- - - - - - +/- - +/- History of alcohal abuse blood ethanol levels +/- Clinical assesment and lab findings
Drug toxicity - -/+ - - +/- - - +/- - +/- - +/- +/- - +/- Medication hx Drug levels - Drug screen test
Metabolic disturbances - -/+ - - - - - - - +/- - - +/- - +/- Underlying CKD, CLD Hypoglycemia, hypo and hypernatremia, hypo and hyperkalemia - Cause dependent
NPH - -/+ - - - - - - - - - - +/- - - OCP use, meds - +/- CT and clinical
Sinusitis - -/+ - - +/- - - - - - - - - - - allergies, seasonal leukocytosis + CT

References

  1. Birenbaum D, Bancroft LW, Felsberg GJ (2011). "Imaging in acute stroke". West J Emerg Med. 12 (1): 67–76. PMC 3088377. PMID 21694755.
  2. DeLaPaz RL, Wippold FJ, Cornelius RS, Amin-Hanjani S, Angtuaco EJ, Broderick DF; et al. (2011). "ACR Appropriateness Criteria® on cerebrovascular disease". J Am Coll Radiol. 8 (8): 532–8. doi:10.1016/j.jacr.2011.05.010. PMID 21807345.
  3. Ho EL, Marra CM (2012). "Treponemal tests for neurosyphilis--less accurate than what we thought?". Sex Transm Dis. 39 (4): 298–9. doi:10.1097/OLQ.0b013e31824ee574. PMC 3746559. PMID 22421697.


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