Guillain-Barré syndrome natural history, complications, and prognosis

Revision as of 16:50, 27 December 2018 by Fahimeh Shojaei (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Guillain-Barré syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Guillain-Barré syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Guillain-Barré syndrome natural history, complications, and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Guillain-Barré syndrome natural history, complications, and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Guillain-Barré syndrome natural history, complications, and prognosis

CDC on Guillain-Barré syndrome natural history, complications, and prognosis

Guillain-Barré syndrome natural history, complications, and prognosis in the news

Blogs on Guillain-Barré syndrome natural history, complications, and prognosis

Directions to Hospitals Treating Guillain-Barré syndrome

Risk calculators and risk factors for Guillain-Barré syndrome natural history, complications, and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Fahimeh Shojaei, M.D.

Overview

The symptoms of Guillain Barre syndrome typically develop 1 to 3 weeks after the Antecedent Infection. If left untreated, 65% of patients with Guillain Barre syndrome will recover with no permanent disability. 35% of them will not fully recover. 8% of these 35% will die from complication and others will have permanent disabilities.

Common complications of GBS include: respiratory failure, autonomic failure, bulbar pulsy, Deep vein thrombosis, Cardiac arrhythmia, Pain, Urinary retention, Ileus and persistent fatigue

Natural History, Complications, and Prognosis

Natural history

  • The symptoms of Guillain Barre syndrome typically develop 1 to 3 weeks after the Antecedent Infection.
  • If left untreated, 65% of patients with Guillain Barre syndrome will recover with no permanent disability.
  • 35% of them will not fully recover. 8% of these 35% will die from complication and others will have permanent disabilities.
  • Treatment will just reduce the recovery period and has no effect on natural history of the disease.
  • The first symptoms are lower extremities weakness and paresthesia.[1][2][3]

Complications

Prognosis

  • About 65% of patients with GBS will fully recover with no permanent disability.
  • 35% of them do not fully recover. 8% of this group will die from GBS complication and others will have permanent disabilities.
  • Treatment of GBS just reduce the recovery time and doesn’t affect prognosis.[6]
  • Overally, older patients will have worst prognosis in comparison to children who discover very fast.[1][2]

References

  1. 1.0 1.1 Hadden RD, Cornblath DR, Hughes RA, Zielasek J, Hartung HP, Toyka KV, Swan AV (November 1998). "Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group". Ann. Neurol. 44 (5): 780–8. doi:10.1002/ana.410440512. PMID 9818934.
  2. 2.0 2.1 Bradshaw DY, Jones HR (April 1992). "Guillain-Barré syndrome in children: clinical course, electrodiagnosis, and prognosis". Muscle Nerve. 15 (4): 500–6. doi:10.1002/mus.880150415. PMID 1565119.
  3. Mattle, Heinrich (2017). Fundamentals of neurology : an illustrated guide. Stuttgart New York: Thieme. ISBN 9783131364524.
  4. Dornonville de la Cour C, Jakobsen J (January 2005). "Residual neuropathy in long-term population-based follow-up of Guillain-Barré syndrome". Neurology. 64 (2): 246–53. doi:10.1212/01.WNL.0000149521.65474.83. PMID 15668421.
  5. Meythaler JM (August 1997). "Rehabilitation of Guillain-Barré syndrome". Arch Phys Med Rehabil. 78 (8): 872–9. PMID 9344309.
  6. Rees JH, Thompson RD, Smeeton NC, Hughes RA (January 1998). "Epidemiological study of Guillain-Barré syndrome in south east England". J. Neurol. Neurosurg. Psychiatry. 64 (1): 74–7. PMC 2169900. PMID 9436731.

Template:WH Template:WS