Guillain-Barré syndrome medical therapy

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Guillain-Barré syndrome Microchapters

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Differentiating Guillain-Barré syndrome from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Supportive therapy for Guillain Barre syndrome include: Respiratory assistance, Heart rate and blood pressure monitoring, prevention of thromboembolic complications by heparin, minimal sedation in intensive care units, pain control and early passive movements. Immunomodulating therapy for Guillain Barre syndrome include: Plasma exchange, High dose immunoglobulin and Corticosteroids.

Medical Therapy

References

  1. "Efficiency of plasma exchange in Guillain-Barré syndrome: role of replacement fluids. French Cooperative Group on Plasma Exchange in Guillain-Barré syndrome". Ann. Neurol. 22 (6): 753–61. December 1987. doi:10.1002/ana.410220612. PMID 2893583.
  2. "Plasma exchange in Guillain-Barré syndrome: one-year follow-up. French Cooperative Group on Plasma Exchange in Guillain-Barré Syndrome". Ann. Neurol. 32 (1): 94–7. July 1992. doi:10.1002/ana.410320115. PMID 1642477.
  3. van der Meché FG, Schmitz PI (April 1992). "A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barré syndrome. Dutch Guillain-Barré Study Group". N. Engl. J. Med. 326 (17): 1123–9. doi:10.1056/NEJM199204233261705. PMID 1552913.
  4. Dalakas MC (December 2002). "Mechanisms of action of IVIg and therapeutic considerations in the treatment of acute and chronic demyelinating neuropathies". Neurology. 59 (12 Suppl 6): S13–21. PMID 12499466.
  5. Heininger K, Schäfer B, Hartung HP, Fierz W, Linington C, Toyka KV (April 1988). "The role of macrophages in experimental autoimmune neuritis induced by a P2-specific T-cell line". Ann. Neurol. 23 (4): 326–31. doi:10.1002/ana.410230403. PMID 3260088.
  6. Hughes RA, Swan AV, van Doorn PA (July 2012). "Intravenous immunoglobulin for Guillain-Barré syndrome". Cochrane Database Syst Rev (7): CD002063. doi:10.1002/14651858.CD002063.pub5. PMID 22786476.
  7. van Koningsveld R, Schmitz PI, Meché FG, Visser LH, Meulstee J, van Doorn PA (January 2004). "Effect of methylprednisolone when added to standard treatment with intravenous immunoglobulin for Guillain-Barré syndrome: randomised trial". Lancet. 363 (9404): 192–6. PMID 14738791.

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