Guillain-Barré syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Incidence vary from 0.4 to 4.0 cases per population of 100 000. In previous studies, Guillain-Barre syndrome mortality rate was 2.58%. It can happen in any age group but it’s more common in late adolescence. The reason behind this is that immune suppressor mechanisms will decrease with age. It was demonstrated in one study that the incidence rate for whites were 0.44 and for blacks were 0.28 per 100,000, but it seems that despite all of these, the incidence is similar across different races. It is more common among males compared to females. Male to female ratio 1.5:1.

Epidemiology and Demographics

Incidence

  • Incidence vary from 0.4 to 4.0 cases per population of 100 000.[1]

Case mortality rate

  • In previous studies, Guillain-Barre syndrome mortality rate was 2.58%.[2]

Age

  • It can happen in any age group but it’s more common in late adolescence.
  • The reason behind this is that immune suppressor mechanisms will decrease with age.[1]

Races

  • It was demonstrated in one study that the incidence rate for whites were 0.44 and for blacks were 0.28 per 100,000, but it seems that despite all of these, the incidence is similar across different races.[3]

Gender

  • It is more common among males compared to females. Male to female ratio 1.5:1.[1]

References

  1. 1.0 1.1 1.2 Hughes RA, Rees JH (December 1997). "Clinical and epidemiologic features of Guillain-Barré syndrome". J. Infect. Dis. 176 Suppl 2: S92–8. PMID 9396689.
  2. Alshekhlee A, Hussain Z, Sultan B, Katirji B (April 2008). "Guillain-Barré syndrome: incidence and mortality rates in US hospitals". Neurology. 70 (18): 1608–13. doi:10.1212/01.wnl.0000310983.38724.d4. PMID 18443311.
  3. Hurwitz ES, Holman RC, Nelson DB, Schonberger LB (February 1983). "National surveillance for Guillain-Barré syndrome: January 1978-March 1979". Neurology. 33 (2): 150–7. PMID 6681655.

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