Guaifenesin: Difference between revisions

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{{DrugProjectFormSinglePage
{{DrugProjectFormSinglePage
|authorTag=<!--Overview-->
|authorTag={{KS}}
|aOrAn=a
|OTC=Yes
|drugClass=
|genericName=guaifenesin
|indicationType=
|aOrAn=an
|indication=
|drugClass=expectorant
|hasBlackBoxWarning=Yes
|indicationType=treatment
|adverseReactions=<!--Black Box Warning-->
|indication=loosening phlegm (mucus) and thinning of bronchial secretions to make coughs more productive.
|adverseReactions=[[nausea]], [[vomiting]]
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
|blackBoxWarningBody=<i><span style="color:#FF0000;">Condition Name:</span></i> (Content)
|fdaLIADAdult===Indications==
* Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.


* Content
==Dosage==
* Follow dosage below or use as directed by a physician.


<!--Adult Indications and Dosage-->
* Do not take more than 6 doses in any 24-hour period.


<!--FDA-Labeled Indications and Dosage (Adult)-->
[[File:guaifenesin table.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
|fdaLIADAdult======Condition1=====
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Guaifenesin in adult patients.
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Guaifenesin in adult patients.
|fdaLIADPed===Indication==


* Dosing Information
* Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.


:* Dosage
==Dosage==


=====Condition2=====
* Follow dosage below or use as directed by a physician.


* Dosing Information
* Do not take more than 6 doses in any 24-hour period.


:* Dosage
[[File:guaifenesin table01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Guaifenesin in pediatric patients.
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Guaifenesin in pediatric patients.
|warnings='''Ask a doctor before use if you have'''


=====Condition3=====
* Cough that occurs with too much phlegm (mucus)
* Cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema


* Dosing Information
'''Stop use and ask a doctor if'''


:* Dosage
Cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.


=====Condition4=====
* You are hypersensitive to any of the ingredients.


* Dosing Information
'''If pregnant or breast-feeding'''


:* Dosage
* Ask a health professional before use.


<!--Off-Label Use and Dosage (Adult)-->
'''Keep out of reach of children'''


<!--Guideline-Supported Use (Adult)-->
* In case of overdose, get medical help or contact a Poison Control Center right away.
|offLabelAdultGuideSupport======Condition1=====
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of Guaifenesin in the drug label.
 
|postmarketing='''Common'''
* Developed by:
Gastrointestinal: [[nausea]], [[vomiting]]
 
|useInPregnancyAUS=There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of guaifenesin in women who are pregnant.
* Class of Recommendation:
|useInLaborDelivery=There is no FDA guidance on use of guaifenesin during labor and delivery.
 
|useInNursing=There is no FDA guidance on the use of guaifenesin with respect to nursing mothers.
* Strength of Evidence:
|useInPed=There is no FDA guidance on the use of guaifenesin with respect to pediatric patients.
 
|useInGeri=There is no FDA guidance on the use of guaifenesin  with respect to geriatric patients.
* Dosing Information
|useInGender=There is no FDA guidance on the use of guaifenesin with respect to specific gender populations.
 
|useInRace=There is no FDA guidance on the use of guaifenesin with respect to specific racial populations.
:* Dosage
|useInRenalImpair=There is no FDA guidance on the use of guaifenesin in patients with renal impairment.
 
|useInHepaticImpair=There is no FDA guidance on the use of guaifenesin in patients with hepatic impairment.
=====Condition2=====
|useInReproPotential=There is no FDA guidance on the use of guaifenesin in women of reproductive potentials and males.
 
|useInImmunocomp=There is no FDA guidance one the use of guaifenesin in patients who are immunocompromised.
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
 
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport======Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
 
<!--Pediatric Indications and Dosage-->
 
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed======Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Off-Label Use and Dosage (Pediatric)-->
 
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Contraindications-->
|contraindications=* Condition1
 
<!--Warnings-->
|warnings=* Description
 
====Precautions====
 
* Description
 
<!--Adverse Reactions-->
 
<!--Clinical Trials Experience-->
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
 
=====Body as a Whole=====
 
 
 
 
=====Cardiovascular=====
 
 
 
 
=====Digestive=====
 
 
 
 
=====Endocrine=====
 
 
 
 
=====Hematologic and Lymphatic=====
 
 
 
 
=====Metabolic and Nutritional=====
 
 
 
 
=====Musculoskeletal=====
 
 
 
 
=====Neurologic=====
 
 
 
 
=====Respiratory=====
 
 
 
 
=====Skin and Hypersensitivy Reactions=====
 
 
 
 
=====Special Senses=====
 
 
 
 
=====Urogenital=====
 
 
 
 
=====Miscellaneous=====
 
 
 
<!--Postmarketing Experience-->
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
 
=====Body as a Whole=====
 
 
 
=====Cardiovascular=====
 
 
 
=====Digestive=====
 
 
 
=====Endocrine=====
 
 
 
=====Hematologic and Lymphatic=====
 
 
 
=====Metabolic and Nutritional=====
 
 
 
=====Musculoskeletal=====
 
 
 
=====Neurologic=====
 
 
 
=====Respiratory=====
 
 
 
=====Skin and Hypersensitivy Reactions=====
 
 
 
=====Special Senses=====
 
 
 
=====Urogenital=====
 
 
 
=====Miscellaneous=====
 
 
 
<!--Drug Interactions-->
|drugInteractions=* Drug
:* Description
 
<!--Use in Specific Populations-->
|FDAPregCat=
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
 
<!--Administration and Monitoring-->
|administration=* Oral
|administration=* Oral
 
|monitoring=There is limited information regarding <i>Monitoring</i> of guaifenesin in the drug label.
* Intravenous
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of guaifenesin in the drug label.
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|PD=There is limited information regarding <i>Pharmacodynamics</i> of guaifenesin in the drug label.
 
|PK=There is limited information regarding <i>Pharmacokinetics</i> of guaifenesin in the drug label.
* Description
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of guaifenesin in the drug label.
 
|storage=* Keep tightly closed. Store at controlled room temperature, 20°-25°C (68°-77°F). [See USP] Protect from light.
<!--IV Compatibility-->
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of guaifenesin in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
|alcohol=* Alcohol-guaifenesin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
 
|brandNames=* GUAIFENESIN
<!--Overdosage-->
|overdose====Acute Overdose===
 
====Signs and Symptoms====
 
* Description
 
====Management====
 
* Description
 
===Chronic Overdose===
 
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.
 
<!--Pharmacology-->
 
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|drugBox=<!--Mechanism of Action-->
|mechAction=*
 
<!--Structure-->
|structure=*
 
: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
 
<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
 
<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.
 
<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.
 
<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.
 
<!--How Supplied-->
|howSupplied=*
|storage=
|packLabel=
<!--Patient Counseling Information-->
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.
 
<!--Precautions with Alcohol-->
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
 
<!--Brand Names-->
|brandNames=* ®<ref>{{Cite web | title =  | url =  }}</ref>
 
<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>
 
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|drugShortage=
|drugShortage=
}}
}}
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|fileName=No image.jpg
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{{LabelImage}}
{{LabelImage
{{LabelImage
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|fileName=Guaifenesin ingredients and appearance.png
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{{LabelImage
{{LabelImage
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|fileName=Guaifenesin fig01.jpg
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<!--Pill Image-->
<!--Pill Image-->
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<!--Category-->
<!--Category-->


[[Category:Uric acid]]
[[Category:Drug]]
[[Category:Drug]]

Latest revision as of 18:39, 9 March 2015

Guaifenesin
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Guaifenesin is an expectorant that is FDA approved for the treatment of loosening phlegm (mucus) and thinning of bronchial secretions to make coughs more productive.. Common adverse reactions include nausea, vomiting.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

  • Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.

Dosage

  • Follow dosage below or use as directed by a physician.
  • Do not take more than 6 doses in any 24-hour period.
This image is provided by the National Library of Medicine.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Guaifenesin in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Guaifenesin in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Indication

  • Helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.

Dosage

  • Follow dosage below or use as directed by a physician.
  • Do not take more than 6 doses in any 24-hour period.
This image is provided by the National Library of Medicine.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Guaifenesin in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Guaifenesin in pediatric patients.

Contraindications

There is limited information regarding Guaifenesin Contraindications in the drug label.

Warnings

Ask a doctor before use if you have

  • Cough that occurs with too much phlegm (mucus)
  • Cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Stop use and ask a doctor if

Cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.

  • You are hypersensitive to any of the ingredients.

If pregnant or breast-feeding

  • Ask a health professional before use.

Keep out of reach of children

  • In case of overdose, get medical help or contact a Poison Control Center right away.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Guaifenesin in the drug label.

Postmarketing Experience

Common Gastrointestinal: nausea, vomiting

Drug Interactions

There is limited information regarding Guaifenesin Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Guaifenesin in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of guaifenesin in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of guaifenesin during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of guaifenesin with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of guaifenesin with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of guaifenesin with respect to geriatric patients.

Gender

There is no FDA guidance on the use of guaifenesin with respect to specific gender populations.

Race

There is no FDA guidance on the use of guaifenesin with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of guaifenesin in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of guaifenesin in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of guaifenesin in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of guaifenesin in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral

Monitoring

There is limited information regarding Monitoring of guaifenesin in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of guaifenesin in the drug label.

Overdosage

There is limited information regarding Guaifenesin overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Guaifenesin Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Guaifenesin Mechanism of Action in the drug label.

Structure

There is limited information regarding Guaifenesin Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of guaifenesin in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of guaifenesin in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of guaifenesin in the drug label.

Clinical Studies

There is limited information regarding Guaifenesin Clinical Studies in the drug label.

How Supplied

There is limited information regarding Guaifenesin How Supplied in the drug label.

Storage

  • Keep tightly closed. Store at controlled room temperature, 20°-25°C (68°-77°F). [See USP] Protect from light.

Images

Drug Images

{{#ask: Page Name::Guaifenesin |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Guaifenesin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of guaifenesin in the drug label.

Precautions with Alcohol

  • Alcohol-guaifenesin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • GUAIFENESIN

Look-Alike Drug Names

There is limited information regarding Guaifenesin Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

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