Goodpasture syndrome physical examination: Difference between revisions

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==Physical Examination==
==Physical Examination==
A complete medical history and comprehensive renal and pulmonary exam must be preformed to help identify and properly diagnose Goodpasture syndrome. A thorough physical examination can provide insight into possible causes and associated underlying conditions. The following findings may be present during a physical examination of Goodpasture syndrome:<ref name="pmid25462583">{{cite journal| author=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G et al.| title=Goodpasture's syndrome: a clinical update. | journal=Autoimmun Rev | year= 2015 | volume= 14 | issue= 3 | pages= 246-53 | pmid=25462583 | doi=10.1016/j.autrev.2014.11.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25462583  }}</ref>
A complete medical history and comprehensive [[renal]] and [[pulmonary]] exam must be performed to help identify and properly diagnose Goodpasture syndrome. A thorough physical examination can provide insight into possible causes and associated underlying conditions. The following findings may be present during a physical examination of Goodpasture syndrome:<ref name="pmid25462583">{{cite journal| author=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G et al.| title=Goodpasture's syndrome: a clinical update. | journal=Autoimmun Rev | year= 2015 | volume= 14 | issue= 3 | pages= 246-53 | pmid=25462583 | doi=10.1016/j.autrev.2014.11.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25462583  }}</ref>
*The presence of tachypnea, inspiratory crackles, edema and hypertension on physical examination are suggestive of presence of renal and pulmonary disorders such as Goodpasture syndrome.
*The presence of [[tachypnea]], inspiratory [[crackles]], [[edema]] and [[hypertension]] on physical examination are suggestive of presence of [[renal]] and [[pulmonary]] disorders such as Goodpasture syndrome.


===Appearance of the Patient===
===Appearance of the Patient===
*Patients with Goodpasture syndrome usually appear fatigued.
*Patients with Goodpasture syndrome usually appear [[Fatigue|fatigued]].


===Vital Signs===
===Vital Signs===
* Low-grade fever
* [[Low-grade fever]]
* [[Tachycardia]]  
* [[Tachycardia]]  
* Tachypnea  
* [[Tachypnea]]
* High blood pressure (advanced renal failure)
* [[High blood pressure]] (advanced [[renal failure]])


===Skin===
===Skin===
* Skin examination of patients with severe Goodpasture syndrome may present with cyanosis from auto-antibodies induced lung tissue injury.
* Skin examination of patients with severe Goodpasture syndrome may present with [[cyanosis]] from [[autoantibodies]] induced lung injury.


===HEENT===
===HEENT===
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===Genitourinary===
===Genitourinary===
* Hematuria may be observed.
* [[Hematuria]] may be observed.


===Extremities===
===Extremities===
* Extremities examination of patients with Goodpasture syndrome may present with:
[[Extremities]] examination of patients with Goodpasture syndrome may present with:
* [[Cyanosis]]  
* [[Cyanosis]]  
*Pitting [[edema]] of the lower extremities
*Pitting [[edema]] of the lower extremities

Latest revision as of 15:01, 1 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3] Akshun Kalia M.B.B.S.[4]

Overview

A complete medical history and comprehensive renal and pulmonary exam must be performed to help identify and properly diagnose Goodpasture syndrome.The presence of tachypnea, inspiratory crackles, edema and hypertension on physical examination are suggestive of presence of renal and pulmonary disorders such as Goodpasture syndrome.

Physical Examination

A complete medical history and comprehensive renal and pulmonary exam must be performed to help identify and properly diagnose Goodpasture syndrome. A thorough physical examination can provide insight into possible causes and associated underlying conditions. The following findings may be present during a physical examination of Goodpasture syndrome:[1]

Appearance of the Patient

  • Patients with Goodpasture syndrome usually appear fatigued.

Vital Signs

Skin

  • Skin examination of patients with severe Goodpasture syndrome may present with cyanosis from autoantibodies induced lung injury.

HEENT

  • HEENT examination of patients with Goodpasture syndrome is usually normal.

Lungs

  • Lungs are hyporresonant
  • Fine Crackles upon auscultation of the lung bases may be present unilaterally/bilaterally

Abdomen

Genitourinary

Extremities

Extremities examination of patients with Goodpasture syndrome may present with:

References

  1. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.

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