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==Historical perspective==
==Historical perspective==
* The exact time of onset of gonorrhea as prevalent disease or epidemic cannot be accurately determined from the historical record.
*Gonorrhea is an ancient disease with Biblical Testament references. However, the exact time of onset of gonorrhea cannot be accurately determined from the historical record.<ref name=History-Gonorreha> Genco, Caroline Attardo. Neisseria: molecular mechanisms of pathogenesis. Horizon Scientific Press, 2010.</ref>
* One of the first reliable notations occur in the Acts of the (English) Parliament. In 1161 this body passed a law to reduce the spread of "...the perilous infirmity of burning." The symptoms described are consistent with, but not diagnostic of, gonorrhea. A similar decree was passed by Louis IX in France in 1256, replacing regulation with banishment. Similar symptoms were noted at the siege of Acre by Crusaders.
* In 1161, One of the first reliable notations occur in the Acts of the (English) Parliament by passing  a law to reduce the spread of "...the perilous infirmity of burning." The symptoms described are consistent with, but not diagnostic of, gonorrhea.<ref name=His> W Sanger. History of Prostitution. NY, Harper, 1910.</ref>
* Coincidental to, or dependent on, the appearance of a gonorrhea epidemic, several changes occurred in European medieval society. Cities hired public health doctors to treat afflicted patients without right of refusal.
*In 1256, A similar decree was passed by Louis IX in France ti reduce the spread of similar symptoms were noted at the siege of Acre by Crusaders.<ref neme=His-2>P. LaCroix. The History of Prostitution—Vol. 2. NY, MacMillan, 1931</ref>
* Pope Boniface rescinded the requirement that physicians complete studies for the lower orders of the Catholic priesthood.
*In 1378, the term “the clap” was first introduced and likely descended from the name of the old Parisian district where prostitutes were housed (Les Clapiers)
* Medieval public health physicians in the employ of their cities were required to treat prostitutes infected with the "burning", as well as lepers and other epidemic victims. After Pope Boniface completely secularized the practice of medicine, physicians were more willing to treat a sexually transmitted disease.
*In 1879, gonorrhea was referred to as “the clap” by German bacteriologist Albert Neisser.<ref name=Gonorrhea> Unemo M, Shafer WM. Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future. Clin Microbiol Rev 2014;27:587–613. </ref>
* It has been suggested that mercury was used as a treatment for gonorrhea.
* Surgeons' tools on board the recovered English warship the Mary Rose included a syringe that, according to some, was used to inject the mercury via the urinary meatus into any unfortunate crewman suffering from gonorrhea.
* The name "the clap", in reference to the disease, is recorded as early as the sixteenth century.
* Silver nitrate was one of the widely used drugs in the 19th century, but it became replaced by Protargol.
* Arthur Eichengrün invented this type of colloidal silver, which was marketed by Bayer from 1897 on.
* The silver-based treatment was used until the first antibiotics came into use in the 1940s


===Historical Perspective of Treatment===
===Historical Perspective of Treatment===
*Historically it has been suggested that [[thermotherapy]], plant-based extracts (cubebs, copaiba), and metals ([[Mercury (element)|mercury]] and [[arsenic]]) were used as a treatment for gonorrhea.<ref name=History-Gonorreha>Genco, Caroline Attardo. Neisseria: molecular mechanisms of pathogenesis. Horizon Scientific Press, 2010.</ref>
*Surgeons tools on board the recovered English warship the ''Mary Rose'' included a [[syringe]] that, according to some, was used to inject the mercury via the [[urinary meatus]] into any unfortunate crewman  in the 19th century, [[Silver nitrate]] was one of the widely used drugs.
*In 1897, [[Silver nitrate]] was replaced by collodial silver after [[Arthur Eichengrün]] invented this type of silver which was marketed by [[Bayer]].
*In 1930s, the first reliable antibiotic (sulfonamides) prove effective against gonorrhea.<ref name=History-Gonorreha>Genco, Caroline Attardo. Neisseria: molecular mechanisms of pathogenesis. Horizon Scientific Press, 2010.</ref>


Historically it has been suggested that [[Mercury (element)|mercury]] was used as a treatment for gonorrhea.  Surgeons tools on board the recovered English warship the ''Mary Rose'' included a [[syringe]] that, according to some, was used to inject the mercury via the [[urinary meatus]] into any unfortunate crewman suffering from gonorrhea. [[Silver nitrate]] was one of the widely used drugs in the 19th century, but it became replaced by Protargol. [[Arthur Eichengrün]] invented this type of collodial silver which was marketed by [[Bayer]] from 1897 on. The silver based treatment was used until the first antibiotics came in use in the 1940's.


==References==
==References==
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[[Category:Sexually transmitted infections|Gonorrhea]]
[[Category:Sexually transmitted infections|Gonorrhea]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]]
[[Category:Mature chapter]]
[[Category:Primary care]]
[[Category:Primary care]]


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{{WH}}
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Revision as of 18:47, 8 September 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]

Overview

The exact time of onset of gonorrhea as prevalent disease or epidemic cannot be accurately determined from the historical record. One of the first reliable notations occur in the Acts of the English Parliament. In 1161 this body passed a law to reduce the spread of gonorrhea. A similar decree was passed by Louis IX in France in 1256, replacing regulation with banishment. Similar symptoms were noted at the siege of Acre by Crusaders.

Historical perspective

  • Gonorrhea is an ancient disease with Biblical Testament references. However, the exact time of onset of gonorrhea cannot be accurately determined from the historical record.[1]
  • In 1161, One of the first reliable notations occur in the Acts of the (English) Parliament by passing a law to reduce the spread of "...the perilous infirmity of burning." The symptoms described are consistent with, but not diagnostic of, gonorrhea.[2]
  • In 1256, A similar decree was passed by Louis IX in France ti reduce the spread of similar symptoms were noted at the siege of Acre by Crusaders.
  • In 1378, the term “the clap” was first introduced and likely descended from the name of the old Parisian district where prostitutes were housed (Les Clapiers)
  • In 1879, gonorrhea was referred to as “the clap” by German bacteriologist Albert Neisser.[3]

Historical Perspective of Treatment

  • Historically it has been suggested that thermotherapy, plant-based extracts (cubebs, copaiba), and metals (mercury and arsenic) were used as a treatment for gonorrhea.[1]
  • Surgeons tools on board the recovered English warship the Mary Rose included a syringe that, according to some, was used to inject the mercury via the urinary meatus into any unfortunate crewman in the 19th century, Silver nitrate was one of the widely used drugs.
  • In 1897, Silver nitrate was replaced by collodial silver after Arthur Eichengrün invented this type of silver which was marketed by Bayer.
  • In 1930s, the first reliable antibiotic (sulfonamides) prove effective against gonorrhea.[1]


References

  1. 1.0 1.1 1.2 Genco, Caroline Attardo. Neisseria: molecular mechanisms of pathogenesis. Horizon Scientific Press, 2010.
  2. W Sanger. History of Prostitution. NY, Harper, 1910.
  3. Unemo M, Shafer WM. Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future. Clin Microbiol Rev 2014;27:587–613.

]

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