Glucagonoma laboratory tests: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
The laboratory findings associated with glucagonoma are:<ref name="pmid15313692" /><ref name="pmid8606627" /><ref name="pmid17873310">{{cite journal| author=Kindmark H, Sundin A, Granberg D, Dunder K, Skogseid B, Janson ET et al.| title=Endocrine [[pancreatic tumors]] with [[glucagon]] hypersecretion: a retrospective study of 23 cases during 20 years. | journal=Med Oncol | year= 2007 | volume= 24 | issue= 3 | pages= 330-7 | pmid=17873310 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17873310  }}</ref>
The laboratory findings associated with glucagonoma are:<ref name="pmid15313692">{{cite journal| author=Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS| title=Clinical experience in diagnosis and treatment of glucagonoma syndrome. | journal=Hepatobiliary Pancreat Dis Int | year= 2004 | volume= 3 | issue= 3 | pages= 473-5 | pmid=15313692 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15313692  }} </ref><ref name="lab">Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma. Accessed on October 15,2015</ref><ref name="pmid15313692" /><ref name="pmid8606627" /><ref name="pmid17873310">{{cite journal| author=Kindmark H, Sundin A, Granberg D, Dunder K, Skogseid B, Janson ET et al.| title=Endocrine [[pancreatic tumors]] with [[glucagon]] hypersecretion: a retrospective study of 23 cases during 20 years. | journal=Med Oncol | year= 2007 | volume= 24 | issue= 3 | pages= 330-7 | pmid=17873310 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17873310  }}</ref>


'''Serum glucagon'''
'''Serum glucagon'''

Revision as of 16:57, 20 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Mohammed Abdelwahed M.D[3]

Overview

Laboratory findings consistent with the diagnosis of glucagonoma include a serum glucagon concentration of 1000 pg/ml or greater.

Laboratory Findings

The laboratory findings associated with glucagonoma are:[1][2][1][3][4]

Serum glucagon

  • Increased plasma glucagon levels >500 pg/mL (Normal glucagon level is less than 50 pg/mL).
  • Concentrations above 1000 pg/mL are diagnostic of glucagonoma.
  • Some conditions can increase glucagon level to a level less than 500 pg/mL such as fasting and hypoglycemia.
  • Some symptomatic glucagonomas are associated with normal glucagon serum level. So, a serum glucagon concentration below 500 pg/mL does not exclude a glucagonoma.[4]

Other laboratory findings

References

  1. 1.0 1.1 Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS (2004). "Clinical experience in diagnosis and treatment of glucagonoma syndrome". Hepatobiliary Pancreat Dis Int. 3 (3): 473–5. PMID 15313692.
  2. Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma. Accessed on October 15,2015
  3. 4.0 4.1 Kindmark H, Sundin A, Granberg D, Dunder K, Skogseid B, Janson ET; et al. (2007). "Endocrine [[pancreatic tumors]] with [[glucagon]] hypersecretion: a retrospective study of 23 cases during 20 years". Med Oncol. 24 (3): 330–7. PMID 17873310. URL–wikilink conflict (help)

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