Glucagonoma laboratory tests: Difference between revisions

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==Overview==
==Overview==
 
Laboratory findings consistent with the diagnosis of glucagonoma include serum glucagon concentration.<ref name="pmid15313692">{{cite journal| author=Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS| title=Clinical experience in diagnosis and treatment of glucagonoma syndrome. | journal=Hepatobiliary Pancreat Dis Int | year= 2004 | volume= 3 | issue= 3 | pages= 473-5 | pmid=15313692 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15313692  }} </ref><ref>Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma</ref>
==Laboratory Findings==
==Laboratory Findings==
 
Laboratory findings consistent with the diagnosis of glucagonoma include:<ref name="pmid15313692">{{cite journal| author=Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS| title=Clinical experience in diagnosis and treatment of glucagonoma syndrome. | journal=Hepatobiliary Pancreat Dis Int | year= 2004 | volume= 3 | issue= 3 | pages= 473-5 | pmid=15313692 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15313692  }} </ref><ref>Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma</ref>
* A [[blood serum]] glucagon concentration of 1000 pg/mL or greater is indicative of glucagonoma (the normal range is 50-200 pg/mL).
* A [[blood serum]] glucagon concentration of 1000 pg/mL or greater is indicative of glucagonoma (the normal range is 50-200 pg/mL).
 
* Blood tests may also reveal abnormally low concentrations of amino acids, [[zinc]], and [[essential fatty acid]]s, which are thought to play a role in the development of Necrolytic migratory erythema.
* Blood tests may also reveal abnormally low concentrations of amino acids, [[zinc]], and [[essential fatty acid]]s, which are thought to play a role in the development of NME.
 
* A [[complete blood count|CBC]] can uncover anemia, which is an abnormally low level of [[hemoglobin]].
* A [[complete blood count|CBC]] can uncover anemia, which is an abnormally low level of [[hemoglobin]].



Revision as of 15:51, 8 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Laboratory findings consistent with the diagnosis of glucagonoma include serum glucagon concentration.[1][2]

Laboratory Findings

Laboratory findings consistent with the diagnosis of glucagonoma include:[1][3]

  • A blood serum glucagon concentration of 1000 pg/mL or greater is indicative of glucagonoma (the normal range is 50-200 pg/mL).
  • Blood tests may also reveal abnormally low concentrations of amino acids, zinc, and essential fatty acids, which are thought to play a role in the development of Necrolytic migratory erythema.
  • A CBC can uncover anemia, which is an abnormally low level of hemoglobin.

References

  1. 1.0 1.1 Zhang M, Xu X, Shen Y, Hu ZH, Wu LM, Zheng SS (2004). "Clinical experience in diagnosis and treatment of glucagonoma syndrome". Hepatobiliary Pancreat Dis Int. 3 (3): 473–5. PMID 15313692.
  2. Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma
  3. Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma


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