Gestational trophoblastic neoplasia natural history, complications and prognosis

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Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Prognosis

  • Most women whose cancer has not spread can be cured and will maintain reproductive function.
  • The condition is harder to cure if the cancer has spread and one of more of the following events occur:
  • Disease has spread to the liver or brain
  • Pregnancy hormone (HCG) level is greater than 40,000 mIU/mL at the time treatment begins
  • Cancer returns after having chemotherapy in the past
  • Symptoms or pregnancy occurred for more than 4 months before treatment began
  • Choriocarcinoma occurred after a pregnancy that resulted in the birth of a child
  • Many women (about 70%) who initially have a poor outlook go into remission (a disease-free state).

Complications

  • A choriocarcinoma may come back after treatment, usually within several months but possibly as late as 3 years.

References

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