Gestational trophoblastic neoplasia natural history, complications and prognosis: Difference between revisions

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==Prognosis==
==Prognosis==
 
The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the lungs are involved.<ref name= abc> General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015</ref>
*Most women whose cancer has not spread can be cured and will maintain reproductive function.
The probability of cure depends on the following:
 
* Histologic type (invasive mole or choriocarcinoma)
*The condition is harder to cure if the cancer has spread and one of more of the following events occur:
* Extent of spread of the disease/largest tumor size
:*Disease has spread to the liver or brain
* Level of serum beta-hCG
:*Pregnancy hormone ([[HCG]]) level is greater than 40,000 mIU/mL at the time treatment begins
* Duration of disease from the initial pregnancy event to start of treatment
:*Cancer returns after having [[chemotherapy]] in the past
* Number and specific sites of metastases
:*Symptoms or pregnancy occurred for more than 4 months before treatment began
* Nature of antecedent pregnancy
:*Choriocarcinoma occurred after a pregnancy that resulted in the birth of a child
* Extent of prior treatment
 
*Many women (about 70%) who initially have a poor outlook go into remission (a disease-free state).


==Complications==
==Complications==

Revision as of 19:39, 14 October 2015

Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural history

Prognosis

The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the lungs are involved.[1] The probability of cure depends on the following:

  • Histologic type (invasive mole or choriocarcinoma)
  • Extent of spread of the disease/largest tumor size
  • Level of serum beta-hCG
  • Duration of disease from the initial pregnancy event to start of treatment
  • Number and specific sites of metastases
  • Nature of antecedent pregnancy
  • Extent of prior treatment

Complications

  • Recurrance
  • Anemia

References

  1. ↑ General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015

Template:WH Template:WS

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