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==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
* The reported incidence of choriocarcinoma in the United States is 2 to 7 per 100,000 pregnancies.<ref name= abc> General Information About Gestational Trophoblastic Disease National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq/#section/_1. Accessed on October7, 2015</ref>
* The reported incidence of choriocarcinoma in the United States is 2 - 7/100,000 pregnancies.<ref name= abc> General Information About Gestational Trophoblastic Disease National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq/#section/_1. Accessed on October7, 2015</ref>
* The U.S. age-standardized (1960 World Population Standard) incidence rate of choriocarcinoma is approximately 0.18/100,000 women between the ages of 15 - 49 years.<ref name="pmid14602247">{{cite journal |vauthors=Altieri A, Franceschi S, Ferlay J, Smith J, La Vecchia C |title=Epidemiology and aetiology of gestational trophoblastic diseases |journal=Lancet Oncol. |volume=4 |issue=11 |pages=670–8 |date=November 2003 |pmid=14602247 |doi= |url=}}</ref>
* The U.S. age-standardized (1960 World Population Standard) incidence rate of choriocarcinoma is approximately 0.18/100,000 women between the ages of 15 - 49 years.<ref name="pmid14602247">{{cite journal |vauthors=Altieri A, Franceschi S, Ferlay J, Smith J, La Vecchia C |title=Epidemiology and aetiology of gestational trophoblastic diseases |journal=Lancet Oncol. |volume=4 |issue=11 |pages=670–8 |date=November 2003 |pmid=14602247 |doi= |url=}}</ref>
*The incidence in Europe ranges from 2 - 3 per 100, 000.<ref name="OlsenMellemkjaer1999">{{cite journal|last1=Olsen|first1=Jørgen H.|last2=Mellemkjaer|first2=Lene|last3=Gridley|first3=Gloria|last4=Brinton|first4=Louise|last5=Johansen|first5=Christoffer|last6=Kjaer|first6=Susanne Krüger|title=Molar pregnancy and risk for cancer in women and their male partners|journal=American Journal of Obstetrics and Gynecology|volume=181|issue=3|year=1999|pages=630–634|issn=00029378|doi=10.1016/S0002-9378(99)70504-1}}</ref><ref name="pmid1322822">{{cite journal |vauthors=Flam F, Lundström-Lindstedt V, Rutqvist LE |title=Incidence of gestational trophoblastic disease in Stockholm County, 1975-1988 |journal=Eur. J. Epidemiol. |volume=8 |issue=2 |pages=173–7 |date=March 1992 |pmid=1322822 |doi= |url=}}</ref><ref name="pmid5519491">{{cite journal |vauthors=Ringertz N |title=Hydatidiform mole, invasive mole and choriocarcinoma in Sweden 1958-1965 |journal=Acta Obstet Gynecol Scand |volume=49 |issue=2 |pages=195–203 |date=1970 |pmid=5519491 |doi= |url=}}</ref>
*The incidence in Europe ranges from 2 - 3/100, 000.<ref name="OlsenMellemkjaer1999">{{cite journal|last1=Olsen|first1=Jørgen H.|last2=Mellemkjaer|first2=Lene|last3=Gridley|first3=Gloria|last4=Brinton|first4=Louise|last5=Johansen|first5=Christoffer|last6=Kjaer|first6=Susanne Krüger|title=Molar pregnancy and risk for cancer in women and their male partners|journal=American Journal of Obstetrics and Gynecology|volume=181|issue=3|year=1999|pages=630–634|issn=00029378|doi=10.1016/S0002-9378(99)70504-1}}</ref><ref name="pmid1322822">{{cite journal |vauthors=Flam F, Lundström-Lindstedt V, Rutqvist LE |title=Incidence of gestational trophoblastic disease in Stockholm County, 1975-1988 |journal=Eur. J. Epidemiol. |volume=8 |issue=2 |pages=173–7 |date=March 1992 |pmid=1322822 |doi= |url=}}</ref><ref name="pmid5519491">{{cite journal |vauthors=Ringertz N |title=Hydatidiform mole, invasive mole and choriocarcinoma in Sweden 1958-1965 |journal=Acta Obstet Gynecol Scand |volume=49 |issue=2 |pages=195–203 |date=1970 |pmid=5519491 |doi= |url=}}</ref>
*The incidence in Canada and Greenland is reported to be approximately 3/100, 000.<ref>{{cite book | last = LastName | first = FirstName | title = Gestational trophoblastic diseases | publisher = World Health Organization | location = Geneva | year = 1983 | isbn = 9241206926 }}</ref><ref name="pmid230189">{{cite journal |vauthors=Nielsen NH, Hansen JP |title=Trophoblastic tumors in Greenland |journal=J. Cancer Res. Clin. Oncol. |volume=95 |issue=2 |pages=177–86 |date=October 1979 |pmid=230189 |doi= |url=}}</ref><ref name="YenMacMahon1968">{{cite journal|last1=Yen|first1=Stella|last2=MacMahon|first2=Brian|title=Epidemiologic features of trophoblastic disease|journal=American Journal of Obstetrics and Gynecology|volume=101|issue=1|year=1968|pages=126–132|issn=00029378|doi=10.1016/0002-9378(68)90497-3}}</ref>
*The reported incidence in Australia is 7/100, 000.<ref>{{cite book | last = LastName | first = FirstName | title = Gestational trophoblastic diseases | publisher = World Health Organization | location = Geneva | year = 1983 | isbn = 9241206926 }}</ref>
*The incidence in Latin America is reported to be 2/100, 000.<ref>{{cite book | last = LastName | first = FirstName | title = Gestational trophoblastic diseases | publisher = World Health Organization | location = Geneva | year = 1983 | isbn = 9241206926 }}</ref><ref name="pmid844972">{{cite journal |vauthors=Sengupta BS, Persaud V, Wynter HH |title=Choriocarcinoma in Jamaica |journal=Int Surg |volume=62 |issue=2 |pages=84–7 |date=February 1977 |pmid=844972 |doi= |url=}}</ref><ref name="pmid226699">{{cite journal |vauthors=Rolon PA, Hochsztajn de Lopez B |title=Malignant trophoblastic disease in paraguay |journal=J Reprod Med |volume=23 |issue=2 |pages=94–6 |date=August 1979 |pmid=226699 |doi= |url=}}</ref>
 
===Prevalence===
===Prevalence===
*The prevalance of choriocarcinoma in the United States is 0.075 - 0.01 per 100, 000.<ref name="pmid6705308">{{cite journal |vauthors=Buckley JD |title=The epidemiology of molar pregnancy and choriocarcinoma |journal=Clin Obstet Gynecol |volume=27 |issue=1 |pages=153–9 |date=March 1984 |pmid=6705308 |doi= |url=}}</ref><ref name="pmid11422477">{{cite journal |vauthors=Burton JL, Lidbury EA, Gillespie AM, Tidy JA, Smith O, Lawry J, Hancock BW, Wells M |title=Over-diagnosis of hydatidiform mole in early tubal ectopic pregnancy |journal=Histopathology |volume=38 |issue=5 |pages=409–17 |date=May 2001 |pmid=11422477 |doi= |url=}}</ref>
*The prevalance of choriocarcinoma in the United States is 0.075 - 0.01 per 100, 000.<ref name="pmid6705308">{{cite journal |vauthors=Buckley JD |title=The epidemiology of molar pregnancy and choriocarcinoma |journal=Clin Obstet Gynecol |volume=27 |issue=1 |pages=153–9 |date=March 1984 |pmid=6705308 |doi= |url=}}</ref><ref name="pmid11422477">{{cite journal |vauthors=Burton JL, Lidbury EA, Gillespie AM, Tidy JA, Smith O, Lawry J, Hancock BW, Wells M |title=Over-diagnosis of hydatidiform mole in early tubal ectopic pregnancy |journal=Histopathology |volume=38 |issue=5 |pages=409–17 |date=May 2001 |pmid=11422477 |doi= |url=}}</ref>

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overveiw

The reported incidence of choriocarcinoma in the United States is 2 to 7 per 100,000 pregnancies. The U.S. age-standardized (1960 World Population Standard) incidence rate of choriocarcinoma is approximately 0.18/100,000 women between the ages of 15 - 49 years.

Epidemiology and Demographics

Incidence

  • The reported incidence of choriocarcinoma in the United States is 2 - 7/100,000 pregnancies.[1]
  • The U.S. age-standardized (1960 World Population Standard) incidence rate of choriocarcinoma is approximately 0.18/100,000 women between the ages of 15 - 49 years.[2]
  • The incidence in Europe ranges from 2 - 3/100, 000.[3][4][5]
  • The incidence in Canada and Greenland is reported to be approximately 3/100, 000.[6][7][8]
  • The reported incidence in Australia is 7/100, 000.[9]
  • The incidence in Latin America is reported to be 2/100, 000.[10][11][12]

Prevalence

  • The prevalance of choriocarcinoma in the United States is 0.075 - 0.01 per 100, 000.[13][14]
  • The prevalence rates from Southeast Asia are 1.5 - 2.5 times higher.[15][16]

References

  1. ↑ General Information About Gestational Trophoblastic Disease National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq/#section/_1. Accessed on October7, 2015
  2. ↑ Altieri A, Franceschi S, Ferlay J, Smith J, La Vecchia C (November 2003). "Epidemiology and aetiology of gestational trophoblastic diseases". Lancet Oncol. 4 (11): 670–8. PMID 14602247.
  3. ↑ Olsen, Jørgen H.; Mellemkjaer, Lene; Gridley, Gloria; Brinton, Louise; Johansen, Christoffer; Kjaer, Susanne Krüger (1999). "Molar pregnancy and risk for cancer in women and their male partners". American Journal of Obstetrics and Gynecology. 181 (3): 630–634. doi:10.1016/S0002-9378(99)70504-1. ISSN 0002-9378.
  4. ↑ Flam F, Lundström-Lindstedt V, Rutqvist LE (March 1992). "Incidence of gestational trophoblastic disease in Stockholm County, 1975-1988". Eur. J. Epidemiol. 8 (2): 173–7. PMID 1322822.
  5. ↑ Ringertz N (1970). "Hydatidiform mole, invasive mole and choriocarcinoma in Sweden 1958-1965". Acta Obstet Gynecol Scand. 49 (2): 195–203. PMID 5519491.
  6. ↑ LastName, FirstName (1983). Gestational trophoblastic diseases. Geneva: World Health Organization. ISBN 9241206926.
  7. ↑ Nielsen NH, Hansen JP (October 1979). "Trophoblastic tumors in Greenland". J. Cancer Res. Clin. Oncol. 95 (2): 177–86. PMID 230189.
  8. ↑ Yen, Stella; MacMahon, Brian (1968). "Epidemiologic features of trophoblastic disease". American Journal of Obstetrics and Gynecology. 101 (1): 126–132. doi:10.1016/0002-9378(68)90497-3. ISSN 0002-9378.
  9. ↑ LastName, FirstName (1983). Gestational trophoblastic diseases. Geneva: World Health Organization. ISBN 9241206926.
  10. ↑ LastName, FirstName (1983). Gestational trophoblastic diseases. Geneva: World Health Organization. ISBN 9241206926.
  11. ↑ Sengupta BS, Persaud V, Wynter HH (February 1977). "Choriocarcinoma in Jamaica". Int Surg. 62 (2): 84–7. PMID 844972.
  12. ↑ Rolon PA, Hochsztajn de Lopez B (August 1979). "Malignant trophoblastic disease in paraguay". J Reprod Med. 23 (2): 94–6. PMID 226699.
  13. ↑ Buckley JD (March 1984). "The epidemiology of molar pregnancy and choriocarcinoma". Clin Obstet Gynecol. 27 (1): 153–9. PMID 6705308.
  14. ↑ Burton JL, Lidbury EA, Gillespie AM, Tidy JA, Smith O, Lawry J, Hancock BW, Wells M (May 2001). "Over-diagnosis of hydatidiform mole in early tubal ectopic pregnancy". Histopathology. 38 (5): 409–17. PMID 11422477.
  15. ↑ Cortes R. Enfenpraded trophoblastic gestational. In obstetrician Clinica. Second edition. Edited by IZigheelboim, D Guariglia. Caracas, Editorial Disinlimed. 2005:374–379.
  16. ↑ Kite NH, Lipscomb GH, Merrill K. Molar corneal ectopic pregnancy. Obstet Gynecol. 2002;99:689–692.

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