Germ cell tumor pathophysiology

• Germ cells are the cells that develop in the embryo and become they make up the reproductive system in males and females.
• After the development of germ cells, they follow the body midline path and descend into the pelvis as ovarian cells or into the scrotal sac as testicular cells.
• Th ovaries and testes are called gonads and many ovarian and testicular tumors have germ cell origin.