Gastrointestinal stromal tumor secondary prevention: Difference between revisions

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{{Gastrointestinal stromal tumor}}
{{Gastrointestinal stromal tumor}}
{{CMG}}; {{AE}}{{Akshun}}
==Overview==
==Overview==
Effective measures for the [[secondary prevention]] of gastrointestinal stromal tumors include regular follow ups including [[physical examination]] with [[laboratory]] and [[imaging]] evaluations. GIST on [[Medicine|medical]] [[therapy]] tend to have a recurrent course and must be evaluated on a periodic basis with an [[CT scan]] or [[PET scan]] for early identification of recurrent [[disease]].


GIST on medical therapy tend to have a recurrent course and must be evaluated on a periodic basis for early identification. Effective measures for the secondary prevention of gastrointestinal stromal tumors include regular follow ups including physical examination with laboratory and imaging evaluations.
==Secondary Prevention==
==Secondary Prevention==
Effective measures for the secondary prevention of gastrointestinal stromal tumors (GIST) include:
Effective measures for the [[secondary prevention]] of gastrointestinal stromal tumors (GIST) include:<ref name="pmid27272772">{{cite journal |vauthors=Vernuccio F, Taibbi A, Picone D, LA Grutta L, Midiri M, Lagalla R, Lo Re G, Bartolotta TV |title=Imaging of Gastrointestinal Stromal Tumors: From Diagnosis to Evaluation of Therapeutic Response |journal=Anticancer Res. |volume=36 |issue=6 |pages=2639–48 |year=2016 |pmid=27272772 |doi= |url=}}</ref>
*Regular follow ups including physical examination with laboratory and imaging evaluations.
*Regular follow ups including [[physical examination]] with [[Medical laboratory|laboratory]] and [[imaging]] evaluations.
**GISTs are known to present with locally recurrent and distant metastasis and thus periodic evaluation through a CT scan should be done for early detection of recurrent disease. However, there is no consensus on the time interval between assessment.
**GISTs are known to present with locally recurrent and distant [[metastasis]] and thus periodic evaluation through a [[CT scan]] should be done for early detection of recurrent [[disease]] and [[Prevention (medical)|prevention]] of future complications (such as [[tumor]] [[hemorrhage]]). However, there is no consensus on the time interval between assessment.
**Patients with indeterminate or inaccessible lesions can be evaluated with PET scans to identify malignant lesions from benign lesions.  
**[[Patient|Patients]] with indeterminate or inaccessible [[Lesion|lesions]] can be evaluated with [[PET scan|PET scans]] to identify [[malignant]] lesions from [[benign]] [[Lesion|lesions]].  
***A positron emission tomography (PET) scanning can also be used to determine response to therapy and can identify active tumor from necrotic and inactive scar tissue. This is particularly helpful in patients receiving tyrosine kinase inhibitor therapy for incompletely resected, recurrent, or metastatic disease.
***A [[positron emission tomography]] ([[PET]]) scanning can also be used to determine response to therapy and can identify active [[tumor]] from [[necrotic]] and inactive [[scar tissue]]. This is particularly helpful in [[Patient|patients]] receiving [[tyrosine kinase inhibitor]] [[therapy]] for incompletely resected, recurrent, or [[metastatic]] [[disease]].


==References==
==References==

Latest revision as of 00:46, 4 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

Effective measures for the secondary prevention of gastrointestinal stromal tumors include regular follow ups including physical examination with laboratory and imaging evaluations. GIST on medical therapy tend to have a recurrent course and must be evaluated on a periodic basis with an CT scan or PET scan for early identification of recurrent disease.

Secondary Prevention

Effective measures for the secondary prevention of gastrointestinal stromal tumors (GIST) include:[1]

References

  1. Vernuccio F, Taibbi A, Picone D, LA Grutta L, Midiri M, Lagalla R, Lo Re G, Bartolotta TV (2016). "Imaging of Gastrointestinal Stromal Tumors: From Diagnosis to Evaluation of Therapeutic Response". Anticancer Res. 36 (6): 2639–48. PMID 27272772.


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