Gallbladder cancer natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Depending on the extent of the tumor at the time of diagnosis, the prognosis is generally regarded as poor.

Natural History

Most tumors are adenocarcinomas, with a small percent being squamous cell carcinomas. The cancer commonly spreads to the liver, pancreas, stomach,and duodenum.

Prognosis

The prognosis is not good for most gallbladder cancer patients if the cancer is detected in its late stages. The prognosis of gallbladder cancer also depends on the following factors:

  • Whether or not the tumor can be removed by surgery
  • The stage of the cancer: the size of the tumor, whether the cancer has spread outside the gallbladder
  • The patient’s general health
  • Whether the cancer has just been diagnosed or has recurred

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