Gallbladder cancer medical therapy: Difference between revisions

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Gallbladder cancer (GBC) is a rare but highly fatal malignancy. The therapy for gallbladder cancer depends largely on the disease progression and the stage of cancer at the time of diagnosis.
Gallbladder cancer (GBC) is a rare but highly fatal malignancy. The therapy for gallbladder cancer depends largely on the disease progression and the stage of cancer at the time of diagnosis.


==Medical Therapy<ref name="pmid17011452">{{cite journal |vauthors=Ben-David MA, Griffith KA, Abu-Isa E, Lawrence TS, Knol J, Zalupski M, Ben-Josef E |title=External-beam radiotherapy for localized extrahepatic cholangiocarcinoma |journal=Int. J. Radiat. Oncol. Biol. Phys. |volume=66 |issue=3 |pages=772–9 |year=2006 |pmid=17011452 |doi=10.1016/j.ijrobp.2006.05.061 |url=}}</ref>==
==Medical Therapy==
There are different types of treatment for patients with gallbladder cancer.
There are different types of treatment for patients with gallbladder cancer.
*The only important curative modality for patients with GBC is surgery
*The only important curative modality for patients with GBC is surgery
*
'''MEDICAL THERAPY FOR OBSTRUCTIVE JAUNDICE'''<ref name="pmid9038546">{{cite journal |vauthors=Kapoor VK, Pradeep R, Haribhakti SP, Singh V, Sikora SS, Saxena R, Kaushik SP |title=Intrahepatic segment III cholangiojejunostomy in advanced carcinoma of the gallbladder |journal=Br J Surg |volume=83 |issue=12 |pages=1709–11 |year=1996 |pmid=9038546 |doi= |url=}}</ref>
*  In 30 to 60 percent of patients with GBC biliary obstruction is the main cause for Jaundice
* Direct infiltration of the common hepatic duct by tumor is the acutall cause
* maximum patients who present with jaundice are normally no longer amenable to a healing resection.
* Biliary or intestinal bypass are considered one of the therapy for palliation of obstructive jaundice
* To relive palliate jaundice and pruritus as little as 30 percent of the liver parenchyma drainage should be neccesary.
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 15:32, 24 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Gallbladder cancer (GBC) is a rare but highly fatal malignancy. The therapy for gallbladder cancer depends largely on the disease progression and the stage of cancer at the time of diagnosis.

Medical Therapy

There are different types of treatment for patients with gallbladder cancer.

  • The only important curative modality for patients with GBC is surgery

MEDICAL THERAPY FOR OBSTRUCTIVE JAUNDICE[1]

  •  In 30 to 60 percent of patients with GBC biliary obstruction is the main cause for Jaundice
  • Direct infiltration of the common hepatic duct by tumor is the acutall cause
  • maximum patients who present with jaundice are normally no longer amenable to a healing resection.
  • Biliary or intestinal bypass are considered one of the therapy for palliation of obstructive jaundice
  • To relive palliate jaundice and pruritus as little as 30 percent of the liver parenchyma drainage should be neccesary.

References

  1. Kapoor VK, Pradeep R, Haribhakti SP, Singh V, Sikora SS, Saxena R, Kaushik SP (1996). "Intrahepatic segment III cholangiojejunostomy in advanced carcinoma of the gallbladder". Br J Surg. 83 (12): 1709–11. PMID 9038546.


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