Free-living amoeba

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1. Free-living amoebic pathogens:
There are 4 genera of free-living amoebas that cause disease in humans:

• Naegleria fowleri (causative pathogen of primary amoebic meningoencephalitis)
• Balamuthia mandrillaris
• Acanthamoeba spp.
• Sappinia spp.

2. Infections caused by free-living amoebas:
Free-living amoebas cause 2 syndromes:

• Primary amoebic meningoencephalitis
• Granulomatous amoebic encephalitis