Fifth disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History and Symptoms

The most common illness caused by parvovirus B19 infection is "fifth disease," a mild rash illness that occurs most often in children. The ill child typically has a "slapped-cheek" rash on the face and a lacy red rash on the trunk and limbs. Occasionally, the rash may itch. The child is usually not very ill, and the rash resolves in 7 to 10 days. Once a child recovers from parvovirus infection, he or she develops lasting immunity, which means that the child is protected against future infection.

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