Fever of unknown origin differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin

Overview

  1. Fever can be the presenting symptom with many diseases, it is therefore important to differentiate fever of unknown origin from all those diseases which present with fever.
  2. Because of the broad range of differential diagnosis they can be grouped into four categories based on their etiology.
  • Infectious
  • Malignant
  • Inflammatory
  • Miscellaneous

Differential diagnosis

Various differential diagnosis of fever of unknown origin include[1][2]

  • Autoinflammatory diseases
  • Malignancy

References

  1. name="pmid28672419">Kümmerle-Deschner JB (2017). "[Autoinflammatory Diseases as a Differential Diagnosis of Fever of Unknown Origin]". Dtsch Med Wochenschr. 142 (13): 969–978. doi:10.1055/s-0043-103468. PMID 28672419.
  2. name="pmid29626024">Fernandez C, Beeching NJ (2018). "Pyrexia of unknown origin". Clin Med (Lond). 18 (2): 170–174. doi:10.7861/clinmedicine.18-2-170. PMC 6303444. PMID 29626024.