Fetal fibronectin

Jump to navigation Jump to search

WikiDoc Resources for Fetal fibronectin

Articles

Most recent articles on Fetal fibronectin

Most cited articles on Fetal fibronectin

Review articles on Fetal fibronectin

Articles on Fetal fibronectin in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Fetal fibronectin

Images of Fetal fibronectin

Photos of Fetal fibronectin

Podcasts & MP3s on Fetal fibronectin

Videos on Fetal fibronectin

Evidence Based Medicine

Cochrane Collaboration on Fetal fibronectin

Bandolier on Fetal fibronectin

TRIP on Fetal fibronectin

Clinical Trials

Ongoing Trials on Fetal fibronectin at Clinical Trials.gov

Trial results on Fetal fibronectin

Clinical Trials on Fetal fibronectin at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Fetal fibronectin

NICE Guidance on Fetal fibronectin

NHS PRODIGY Guidance

FDA on Fetal fibronectin

CDC on Fetal fibronectin

Books

Books on Fetal fibronectin

News

Fetal fibronectin in the news

Be alerted to news on Fetal fibronectin

News trends on Fetal fibronectin

Commentary

Blogs on Fetal fibronectin

Definitions

Definitions of Fetal fibronectin

Patient Resources / Community

Patient resources on Fetal fibronectin

Discussion groups on Fetal fibronectin

Patient Handouts on Fetal fibronectin

Directions to Hospitals Treating Fetal fibronectin

Risk calculators and risk factors for Fetal fibronectin

Healthcare Provider Resources

Symptoms of Fetal fibronectin

Causes & Risk Factors for Fetal fibronectin

Diagnostic studies for Fetal fibronectin

Treatment of Fetal fibronectin

Continuing Medical Education (CME)

CME Programs on Fetal fibronectin

International

Fetal fibronectin en Espanol

Fetal fibronectin en Francais

Business

Fetal fibronectin in the Marketplace

Patents on Fetal fibronectin

Experimental / Informatics

List of terms related to Fetal fibronectin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Fetal fibronectin (fFN) is a protein produced by fetal cells and a type of fibronectin. fFN is found at the interface of the chorion and the decidua (between the fetal sack and the uterine lining).

It can be thought of as an adhesive or "biological glue" that binds the fetal sack to the uterine lining. It is an excellent biological marker of premature (preterm) delivery; a delivery before 37 weeks of gestation.

Fetal fibronectin "leaks" into the vagina if a preterm delivery is likely to occur and can be measured in a diagnostic test. When the fFN test is considered positive, delivery is likely to occur soon. When the fFN test is negative, it means that there is little if any danger of preterm labour for 7-10 days. The test is easily performed. A specimen is collected from the patient using a vaginal swab. The swab is placed in a transport tube and sent to the lab for testing. The lab can easily produce a test result in less than one hour.

A systematic review of the medical literature found that fetal fibronectin is a good predictor of spontaneous preterm birth before cervical dilation.[1] The test may be run on patients between 22 and 35 weeks gestation.

References

  1. Honest H, Bachmann LM, Gupta JK, Kleijnen J, Khan KS. Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review. BMJ. 2002 Aug 10;325(7359):301. PMID 12169504. Free Full Text.

Template:SIB

Template:WH Template:WikiDoc Sources