Fat embolism syndrome laboratory findings: Difference between revisions

Jump to navigation Jump to search
No edit summary
Line 6: Line 6:


==Laboratory Findings==
==Laboratory Findings==
Plasma PLA2 (phospholipase A2), nitrate/nitrite, methylguanidine, TNF-α (tumour necrosis factor-α), IL-1β (interleukin-1β) and IL-10 (interleukin-10) were significantly elevated
Fat embolism syndrome is associated with elevations in the following laboratory values:
 
* Plasma PLA2 (phospholipase A2)
* Nitrate/nitrite
* Methylguanidine
* TNF-α (tumour necrosis factor-α)
* IL-1β (interleukin-1β)  
* IL-10 (interleukin-10)  
The recovery of fat from pulmonary artery (PA) catheter wedged blood, [[sputum]] and [[urine]] is nonspecific.  One study found fat in 50% of sera from patients with long bone fractures who had no evidence of FES.  [[Bronchoscopy]] and [[bronchoalveolar lavage]] (BAL) seem to be more specific by demonstrating fat droplets in alveolar [[macrophages]].
The recovery of fat from pulmonary artery (PA) catheter wedged blood, [[sputum]] and [[urine]] is nonspecific.  One study found fat in 50% of sera from patients with long bone fractures who had no evidence of FES.  [[Bronchoscopy]] and [[bronchoalveolar lavage]] (BAL) seem to be more specific by demonstrating fat droplets in alveolar [[macrophages]].



Revision as of 20:04, 21 February 2018

Fat embolism syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Fat embolism syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Fat embolism syndrome laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Fat embolism syndrome laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Fat embolism syndrome laboratory findings

CDC on Fat embolism syndrome laboratory findings

Fat embolism syndrome laboratory findings in the news

Blogs on Fat embolism syndrome laboratory findings

Directions to Hospitals Treating Fat embolism syndrome

Risk calculators and risk factors for Fat embolism syndrome laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

Laboratory Findings

Fat embolism syndrome is associated with elevations in the following laboratory values:

  • Plasma PLA2 (phospholipase A2)
  • Nitrate/nitrite
  • Methylguanidine
  • TNF-α (tumour necrosis factor-α)
  • IL-1β (interleukin-1β)
  • IL-10 (interleukin-10)

The recovery of fat from pulmonary artery (PA) catheter wedged blood, sputum and urine is nonspecific. One study found fat in 50% of sera from patients with long bone fractures who had no evidence of FES. Bronchoscopy and bronchoalveolar lavage (BAL) seem to be more specific by demonstrating fat droplets in alveolar macrophages.

References