Familial amyloidosis surgery: Difference between revisions
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==Overview== | ==Overview== | ||
[[Organ transplant|Organ-specific transplant]] may need to be done, depending on the organ involved. However, [[surgery]] is not commonly done in patients with amyloidosis, since it is usually a systemic disease that requires treatment of the underlying cause. | [[Organ transplant|Organ-specific transplant]] may need to be done, depending on the organ involved. However, [[surgery]] is not commonly done in patients with amyloidosis, since it is usually a systemic disease that requires treatment of the underlying cause. | ||
== Indications == | |||
The mainstay of treatment for familial amyloidosis is eradicating the underlying cause. Surgery is usually reserved for patients with organ failure such as:<ref name="pmid23227279">{{cite journal| author=Estep JD, Bhimaraj A, Cordero-Reyes AM, Bruckner B, Loebe M, Torre-Amione G| title=Heart transplantation and end-stage cardiac amyloidosis: a review and approach to evaluation and management. | journal=Methodist Debakey Cardiovasc J | year= 2012 | volume= 8 | issue= 3 | pages= 8-16 | pmid=23227279 | doi= | pmc=3487570 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23227279 }} </ref> | |||
* Heart failure | |||
* Chronic renal disease | |||
* Liver failure | |||
==Surgery== | ==Surgery== | ||
*[[Cardiac transplantation|Cardiac transplant]] may need to be done for patients with cardiac amyloidosis. | *[[Cardiac transplantation|Cardiac transplant]] may need to be done for patients with cardiac amyloidosis. | ||
*[[Organ transplant|Organ-specific transplant]] may need to be done, depending on the [[Organ (anatomy)|organ]] involved. | *[[Organ transplant|Organ-specific transplant]] may need to be done, depending on the [[Organ (anatomy)|organ]] involved. | ||
Latest revision as of 04:08, 21 November 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Organ-specific transplant may need to be done, depending on the organ involved. However, surgery is not commonly done in patients with amyloidosis, since it is usually a systemic disease that requires treatment of the underlying cause.
Indications
The mainstay of treatment for familial amyloidosis is eradicating the underlying cause. Surgery is usually reserved for patients with organ failure such as:[1]
- Heart failure
- Chronic renal disease
- Liver failure
Surgery
- Cardiac transplant may need to be done for patients with cardiac amyloidosis.
- Organ-specific transplant may need to be done, depending on the organ involved.