FZD10

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Frizzled-10 is a protein that in humans is encoded by the FZD10 gene.[1][2] FZD10 has also been designated as CD350 (cluster of differentiation 350).

Function

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[2]

See also

References

  1. Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Aug 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochemical and Biophysical Research Communications. 262 (1): 39–43. doi:10.1006/bbrc.1999.1161. PMID 10448064.
  2. 2.0 2.1 "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.