FMC-R regimen: Difference between revisions
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{{SI}} | {{SI}} {{CMG}}; {{AE}} {{AV}} | ||
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{{SK}}R- | {{SK}}FCMR Regimen; R-FCM Regimen; Rituximab-Fludarabine-Cyclophosphamide-Mitoxantrone Regimen | ||
==Overview== | ==Overview== | ||
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==Indications== | ==Indications== | ||
*[[ | *Indolent [[non-Hodgkin's lymphoma]] and relapsed or refractory [[mantle cell lymphoma]].<ref>{{Cite web | title = NCI Thesaurus | accessdate = | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C63463&ns=NCI_Thesaurus}}</ref> | ||
*[[CLL]]<ref name="pmid19646755">{{cite journal| author=Faderl S, Wierda W, O'Brien S, Ferrajoli A, Lerner S, Keating MJ| title=Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years. | journal=Leuk Res | year= 2010 | volume= 34 | issue= 3 | pages= 284-8 | pmid=19646755 | doi=10.1016/j.leukres.2009.07.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19646755 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Chemotherapy regimens]] | [[Category:Chemotherapy regimens]] | ||
Revision as of 16:24, 31 March 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]
Synonyms and keywords:FCMR Regimen; R-FCM Regimen; Rituximab-Fludarabine-Cyclophosphamide-Mitoxantrone Regimen
Overview
FMC-R regimen refers to a regimen consisting of fludarabine, mitoxantrone, cyclophosphamide and rituximab, used in the treatment of resistant or relapsed chronic lymphocytic leukaemia.[1]
Regimen
FFludarabine
MMitoxantrone
CCyclophosphamide
RRituximab
Indications
- Indolent non-Hodgkin's lymphoma and relapsed or refractory mantle cell lymphoma.[2]
- CLL[3]
References
- ↑ Forstpointner R, Dreyling M, Repp R, Hermann S, Hänel A, Metzner B; et al. (2004). "The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group". Blood. 104 (10): 3064–71. doi:10.1182/blood-2004-04-1323. PMID 15284112.
- ↑ "NCI Thesaurus".
- ↑ Faderl S, Wierda W, O'Brien S, Ferrajoli A, Lerner S, Keating MJ (2010). "Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years". Leuk Res. 34 (3): 284–8. doi:10.1016/j.leukres.2009.07.008. PMID 19646755.