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{{Eosinophilic pneumonia}}
{{Eosinophilic pneumonia}}
{{CMG}} {{AE}} [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com]
{{CMG}} {{AE}} {{MAD}}


==Overview==
==Overview==
'''Eosinophilic pneumonia''' ('''EP''') is a [[disease]] in which a certain type of [[white blood cell]] called an [[eosinophil]] accumulates in the [[lung]]. These cells cause disruption of the normal air spaces ([[alveoli]]) where [[oxygen]] is extracted from the [[Earth's atmosphere|atmosphere]]. Several different kinds of eosinophilic pneumonia exist and can occur in any age group. The most common [[symptom]]s include [[cough]], [[fever]], [[dyspnea|difficulty breathing]], and sweating at night. EP is diagnosed by a combination of characteristic symptoms, findings on a [[physical examination]] by a health provider, and the results of [[medical laboratory|blood tests]] and [[radiology|x-rays]]. [[Prognosis]] is excellent once most EP is recognized and treatment with [[corticosteroid]]s is begun.
Onset of chronic type is more than 2–4 weeks and acute one is less than 1 month. A history of [[atopy]] is found in 60 percent. Symptoms of idiopathic eosinophilic pneumonia include [[dyspnea]], [[fever]], c[[Cough|ough]], [[wheezing]], [[sputum]], [[Myalgia|myalgias]].


== History and Symptoms ==
== History ==
Most causes of eosinophilic pneumonia have similar symptoms. [[Cough]], [[fever]], [[dyspnea|increasing breathlessness]], and [[Sleep hyperhidrosis|night sweats]] are prominent and almost universal. Acute eosinophilic pneumonia typically follows a rapid course. Fever and cough may develop only one or two weeks before difficulties breathing progress to the point of [[respiratory failure]] requiring mechanical [[Medical ventilator|ventilation]]. Chronic eosinophilic pneumonia usually follows a slower course. Symptoms accumulate over several months and include fevers, cough, breathlessness, wheezing, and weight loss. Individuals with CEP are often diagnosed with [[asthma]] before CEP is finally recognized.  
* [[Eosinophilia|Chronic eosinophilia]] affects patients in their 30s or 40s.<ref name="pmid12882444">{{cite journal| author=Marchand E, Etienne-Mastroianni B, Chanez P, Lauque D, Leclerc P, Cordier JF et al.| title=Idiopathic chronic eosinophilic pneumonia and asthma: how do they influence each other? | journal=Eur Respir J | year= 2003 | volume= 22 | issue= 1 | pages= 8-13 | pmid=12882444 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12882444  }}</ref> 
* A history of [[atopy]] is found in 60 percent.
* Onset of chronic type is more than 2–4 weeks and acute one is less than 1 month.
* History of [[asthma]] with chronic type. 
* Smoking history is more evident with the acute type.


EP due to medications or environmental exposures is similar and occurs after an exposure to a known offending agent. EP due to parasitic infections has a similar [[prodrome]] in addition to a host of different symptoms related to the variety of underlying parasites. EP in the setting of cancer often develops in the context of a known diagnosis of lung cancer, cervical cancer, etc.
== Symptoms ==
Symptoms of idiopathic eosinophilic pneumonia include:<ref name="pmid97729202">{{cite journal| author=Marchand E, Reynaud-Gaubert M, Lauque D, Durieu J, Tonnel AB, Cordier JF| title=Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P). | journal=Medicine (Baltimore) | year= 1998 | volume= 77 | issue= 5 | pages= 299-312 | pmid=9772920 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9772920  }}</ref><ref name="pmid25614171">{{cite journal| author=Oyama Y, Fujisawa T, Hashimoto D, Enomoto N, Nakamura Y, Inui N et al.| title=Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia. | journal=Eur Respir J | year= 2015 | volume= 45 | issue= 6 | pages= 1624-31 | pmid=25614171 | doi=10.1183/09031936.00199614 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25614171  }}</ref><ref name="pmid22599359">{{cite journal| author=Rhee CK, Min KH, Yim NY, Lee JE, Lee NR, Chung MP et al.| title=Clinical characteristics and corticosteroid treatment of acute eosinophilic pneumonia. | journal=Eur Respir J | year= 2013 | volume= 41 | issue= 2 | pages= 402-9 | pmid=22599359 | doi=10.1183/09031936.00221811 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22599359  }}</ref>
* Acute onset of [[dyspnea]]
* [[Fever]] that is usually moderate
* [[Cough]]
* [[Wheezing]]
* blood-tinged [[sputum]]
* pleuritic thoracic pain
* [[Myalgia|Myalgias]]
* Acute [[respiratory failure]] is frequent in the acute pneumonia and mechanical ventilation


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Pulmonology]]
[[Category:Emergency medicine]]
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]

Overview

Onset of chronic type is more than 2–4 weeks and acute one is less than 1 month. A history of atopy is found in 60 percent. Symptoms of idiopathic eosinophilic pneumonia include dyspnea, fever, cough, wheezing, sputum, myalgias.

History

  • Chronic eosinophilia affects patients in their 30s or 40s.[1]
  • A history of atopy is found in 60 percent.
  • Onset of chronic type is more than 2–4 weeks and acute one is less than 1 month.
  • History of asthma with chronic type.
  • Smoking history is more evident with the acute type.

Symptoms

Symptoms of idiopathic eosinophilic pneumonia include:[2][3][4]

References

  1. Marchand E, Etienne-Mastroianni B, Chanez P, Lauque D, Leclerc P, Cordier JF; et al. (2003). "Idiopathic chronic eosinophilic pneumonia and asthma: how do they influence each other?". Eur Respir J. 22 (1): 8–13. PMID 12882444.
  2. Marchand E, Reynaud-Gaubert M, Lauque D, Durieu J, Tonnel AB, Cordier JF (1998). "Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P)". Medicine (Baltimore). 77 (5): 299–312. PMID 9772920.
  3. Oyama Y, Fujisawa T, Hashimoto D, Enomoto N, Nakamura Y, Inui N; et al. (2015). "Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia". Eur Respir J. 45 (6): 1624–31. doi:10.1183/09031936.00199614. PMID 25614171.
  4. Rhee CK, Min KH, Yim NY, Lee JE, Lee NR, Chung MP; et al. (2013). "Clinical characteristics and corticosteroid treatment of acute eosinophilic pneumonia". Eur Respir J. 41 (2): 402–9. doi:10.1183/09031936.00221811. PMID 22599359.

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