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| {{drugbox
| | #REDIRECT [[Dicyclomine]] |
| | IUPAC_name = 2-diethylaminoethyl1- cyclohexylcyclohexane- 1-carboxylate
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| | image = dicyclomine-trans.png
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| | CAS_number = 77-19-0
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| | ATC_prefix = A03
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| | ATC_suffix = AA07
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| | ATC_supplemental =
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| | PubChem = 3042
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| | DrugBank = APRD00113
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| | C=19 | H=35 | N=1 | O=2
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| | molecular_weight = 309.487 g/mol
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| | bioavailability =
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| | protein_bound = >99%
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| | metabolism =
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| | elimination_half-life =
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| | excretion =
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| | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
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| | pregnancy_US = <!-- A / B / C / D / X -->
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| | pregnancy_category =
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| | legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
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| | legal_UK = <!-- GSL / P / POM / CD -->
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| | legal_US = <!-- OTC / Rx-only -->
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| | legal_status =
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| | routes_of_administration =
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| }}
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| '''Dicyclomine''' is an [[anticholinergic]] that blocks [[muscarinic acetylcholine receptor|muscarinic receptors]]. Dicyclomine is known as dicycloverine hydrochloride in the UK.
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| ==Clinical uses==
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| Dicyclomine is used to treat [[intestinal hypermotility]], the symptoms of [[Irritable Bowel Syndrome]] (IBS) (also known as spastic colon). It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body. It is a smooth muscle relaxer.
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| In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.
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| It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada.
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| ==Sources==
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| *Brenner, G. M. (2000). ''Pharmacology.'' Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
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| *Canadian Pharmacists Association (2000). ''Compendium of Pharmaceuticals and Specialties'' (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4
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| ==External links==
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| * [http://www.medicinenet.com/dicyclomine/article.htm Dicyclomine] on Medicine Net
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| * [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a684007.html Dicyclomine] on Medline Plus
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| {{Drugs for functional gastrointestinal disorders }}
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| [[Category:Muscarinic antagonists]]
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