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==Diabetic foot infection==
DFI is classified based on its severity according to the Infectious Diseases Society of America (IDSA) guideline or the PEDIS grade developed by International Working Group on the Diabetic Foot (IWGDF).<ref name="pmid22619242">{{cite journal| author=Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJ, Armstrong DG et al.| title=2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. | journal=Clin Infect Dis | year= 2012 | volume= 54 | issue= 12 | pages= e132-73 | pmid=22619242 | doi=10.1093/cid/cis346 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22619242 }} </ref>
 
{|
| style="width: 15px;"|
|
{| style="border: 2px solid #DCDCDC; font-size: 90%;"
! align="center" style="background: #DCDCDC;" | '''Clinical Manifestation'''
! align="center" style="background: #DCDCDC; padding: 0 10px;" | '''PEDIS Grade'''
! align="center" style="background: #DCDCDC; padding: 0 10px;" | '''IDSA Severity'''
|-
| style="background: #F5F5F5; padding: 0 10px;" | '''No symptoms or signs of infection'''
! style="background: #F5F5F5; padding: 0 10px;" | 1
! style="background: #F5F5F5; padding: 0 10px;" | Uninfected
|-
| style="background: #F5F5F5; padding: 0 10px;" | '''Local infection involving only the skin and the subcutaneous tissue''' <u>without</u> involvement of deeper tissues and <u>without</u> signs of SIRS
* If erythema, must be >0.5 cm to ≤2 cm around the ulcer.
* Exclude other causes of an inflammatory response of the skin (eg, trauma, gout, acute Charcot neuro-osteoarthropathy, fracture, thrombosis, venous stasis).
! style="background: #F5F5F5; padding: 0 10px;" | 2
! style="background: #F5F5F5; padding: 0 10px;" | Mild
|-
| style="background: #F5F5F5; padding: 0 10px;" | '''Local infection with erythema >2 cm or involving structures deeper than skin and subcutaneous tissues''' (eg, abscess, osteomyelitis, septic arthritis, fasciitis) <u>without</u> signs of SIRS
! style="background: #F5F5F5; padding: 0 10px;" | 3
! style="background: #F5F5F5; padding: 0 10px;" | Moderate
|-
| style="background: #F5F5F5; padding: 0 10px;" | '''Local infection with the signs of SIRS''', as manifested by ≥2 of the following:
* Temperature &gt;38 °C or &lt;36 °C
* Heart rate &gt;90 beats/min
* Respiratory rate &gt;20 breaths/min or PaCO2 &lt;32 mm Hg
* White blood cell count &gt;12,000 or &lt;4,000 cells/μL or ≥10% immature (band) forms
! style="background: #F5F5F5; padding: 0 10px;" | 4
! style="background: #F5F5F5; padding: 0 10px;" | Severe
|}
|}
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 18:33, 2 June 2014

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Diabetic foot infection

DFI is classified based on its severity according to the Infectious Diseases Society of America (IDSA) guideline or the PEDIS grade developed by International Working Group on the Diabetic Foot (IWGDF).[1]

Clinical Manifestation PEDIS Grade IDSA Severity
No symptoms or signs of infection 1 Uninfected
Local infection involving only the skin and the subcutaneous tissue without involvement of deeper tissues and without signs of SIRS
  • If erythema, must be >0.5 cm to ≤2 cm around the ulcer.
  • Exclude other causes of an inflammatory response of the skin (eg, trauma, gout, acute Charcot neuro-osteoarthropathy, fracture, thrombosis, venous stasis).
2 Mild
Local infection with erythema >2 cm or involving structures deeper than skin and subcutaneous tissues (eg, abscess, osteomyelitis, septic arthritis, fasciitis) without signs of SIRS 3 Moderate
Local infection with the signs of SIRS, as manifested by ≥2 of the following:
  • Temperature >38 °C or <36 °C
  • Heart rate >90 beats/min
  • Respiratory rate >20 breaths/min or PaCO2 <32 mm Hg
  • White blood cell count >12,000 or <4,000 cells/μL or ≥10% immature (band) forms
4 Severe

References

  1. Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJ, Armstrong DG; et al. (2012). "2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections". Clin Infect Dis. 54 (12): e132–73. doi:10.1093/cid/cis346. PMID 22619242.

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