Desmoid tumor medical therapy: Difference between revisions

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{{CMG}} {{AE}}{{Faizan}}
{{CMG}} {{AE}}{{Faizan}}
==Overview==
==Overview==
Medical therapy for desmoid tumor includes [[antiestrogen]]s (ex. [[tamoxifen]]), [[non-steroidal anti-inflammatory drug|NSAIDs]], [[chemotherapy]] or microwave ablation.
Medical therapy for desmoid tumor includes [[antiestrogen]]s (ex. [[tamoxifen]]), [[non-steroidal anti-inflammatory drug|NSAIDs]], [[chemotherapy]], or microwave ablation.


==Medical Therapy==
==Medical Therapy==
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*[[Chemotherapy]]
*[[Chemotherapy]]
*Microwave ablation
*Microwave ablation
Current experimental studies are being done with Gleevec ([[Imatinib]]) and Nexavar ([[sorafenib]]) for treatment of desmoid tumors, and show promising success rates.


==Radiation Therapy==
==Radiation Therapy==
Rarely, [[radiation therapy]] is used if medical therapy and [[surgery]] fail.  Depending on the size and location of the [[tumor]], [[radiation]] is delivered either in low doses  over the course of 5 to 6 weeks or in a single high dose. [[Radiation]] therapy is effective in approximately 30% of cases.
Rarely, [[radiation therapy]] is used if medical therapy and [[surgery]] fail.  Depending on the size and location of the [[tumor]], [[radiation]] is delivered either in low doses  over the course of 5 to 6 weeks or in a single high dose. [[Radiation]] therapy is effective in approximately 30% of cases.


==Reference==
==Reference==

Revision as of 19:41, 26 January 2016

Desmoid tumor Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Desmoid tumor from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

Medical therapy for desmoid tumor includes antiestrogens (ex. tamoxifen), NSAIDs, chemotherapy, or microwave ablation.

Medical Therapy

Medical therapy for prolactinoma includes:[1][2]

Radiation Therapy

Rarely, radiation therapy is used if medical therapy and surgery fail. Depending on the size and location of the tumor, radiation is delivered either in low doses over the course of 5 to 6 weeks or in a single high dose. Radiation therapy is effective in approximately 30% of cases.

Reference

  1. Wilkinson MJ, Fitzgerald JE, Thomas JM, Hayes AJ, Strauss DC (2012). "Surgical resection for non-familial adenomatous polyposis-related intra-abdominal fibromatosis". BJS. 99 (5): 706–13. doi:10.1002/bjs.8703. PMID 22359346.
  2. Rammohan A, Wood JJ (2012). "Desmoid tumour of the breast as a manifestation of Gardner's syndrome". Int J Surg Case Rep. 3 (5): 139–42. doi:10.1016/j.ijscr.2012.01.004. PMC 3312056. PMID 22370045.

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