Desmoid tumor future or investigational therapies: Difference between revisions

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===Angiogenesis inhibitors===
===Angiogenesis inhibitors===
*Newer substances that may be able to prevent the growth of tumors by blocking the formation of new blood vessels that feed the tumors are being currently investigated.
*Newer substances that may be able to prevent the growth of tumors by blocking the formation of new blood vessels that feed the tumors are being currently investigated


===Chemotherapy agents===
===Chemotherapy agents===
*Researchers are also testing several chemotherapy drugs, or combination of drugs, that could prove to be most effective in treating desmoid tumors to avoid radical management via surgery.
*Researchers are also testing several chemotherapy drugs, or combination of drugs, that could prove to be most effective in treating desmoid tumors to avoid radical management via surgery


===Mutations in the gene for beta-catenin===
===Mutations in the gene for beta-catenin===
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*Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov
*Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov
*National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/
*National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/





Revision as of 18:32, 4 March 2019

Desmoid tumor Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Desmoid tumor from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

Future or Investigational therapies

  • Following investigational therapies might prove fruitful in future for treatment of desmoid tumors:

Angiogenesis inhibitors

  • Newer substances that may be able to prevent the growth of tumors by blocking the formation of new blood vessels that feed the tumors are being currently investigated

Chemotherapy agents

  • Researchers are also testing several chemotherapy drugs, or combination of drugs, that could prove to be most effective in treating desmoid tumors to avoid radical management via surgery

Mutations in the gene for beta-catenin

  • These mutations have been found to commonly occur in desmoid tumor
  • Mutation analysis may soon be used to predict the risk of recurrence and to aid in the design of individual therapies

Source



Reference

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