Creutzfeldt-Jakob disease historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
Historical Perspective
- Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
- The term Creutzfeldt Jakob was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob's report.[1]
- In 1997, Stanley B. Prusiner was awarded the Nobel Prize in physiology or medicine for his discovery of prions.
- In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a virus-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human Creutzfeldt Jakob disease agent.[2]
References
- ↑ McKintosh, E.; Tabrizi, SJ.; Collinge, J. (2003). "Prion diseases". J Neurovirol. 9 (2): 183–93. doi:10.1080/13550280390194082. PMID 12707849. Unknown parameter
|month=ignored (help) - ↑ Manuelidis L (February 6, 2007). "Cells infected with scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles". Proceedings of the National Academy of Science. 104 (6): 1975–1970. PMID 17267596. Retrieved 2007-09-24. Unknown parameter
|coauthors=ignored (help)