Craniopharyngioma natural history, complication and prognosis

Revision as of 19:52, 19 February 2019 by Marjan Khan (talk | contribs)
Jump to navigation Jump to search

Craniopharyngioma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Craniopharyngioma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Craniopharyngioma natural history, complication and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Craniopharyngioma natural history, complication and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Craniopharyngioma natural history, complication and prognosis

CDC on Craniopharyngioma natural history, complication and prognosis

Craniopharyngioma natural history, complication and prognosis in the news

Blogs on Craniopharyngioma natural history, complication and prognosis

Directions to Hospitals Treating Craniopharyngioma

Risk calculators and risk factors for Craniopharyngioma natural history, complication and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]

Overview

If left untreated, majority of patients with craniopharyngioma may progress to develop increased intracranial pressure, blindness and endocrine abnormalities. The prognosis of craniopharyngioma is good with treatment. The 5-year and 10-year survival rates are higher than 90%.

Natural History

  • Craniopharyngiomas are slow growing tumors and symptoms often are present for a year or more before the diagnosis is established.[1]
  • Untreated patients can have increased intracranial pressure, visual disturbances and endocrine abnormalities.

Complications

A large percentage of patients have long-term hormone, vision, and nervous system problems after craniopharyngioma is treated. When the tumor is not completely removed, the condition may recur.[2]

There are complications caused by the radical surgical treatment of craniopharyngioma:[3]

Prognosis

  • Craniopharyngioma is a benign tumor, the 5-year and 10-year survival rates, regardless of treatment given, are higher than 90%. [5]
  • Patients can have a permanent cure if the tumor can be completely removed with surgery or treated with high doses of radiation.[6]
  • The outlook depends on whether or not the tumor can be removed by surgery.
  • The neurological deficits and hormonal imbalances caused by the tumor and the treatment The patient’s general health
  • Recent research has demonstrated malignant tendency of craniopharyngiomas.
  • These malignant craniopharyngiomas are very rare, but are associated with poor prognosis.[7]

References

  1. Wijnen M, van den Heuvel-Eibrink MM, Janssen J, Catsman-Berrevoets CE, Michiels E, van Veelen-Vincent MC, Dallenga A, van den Berge JH, van Rij CM, van der Lely AJ, Neggers S (June 2017). "Very long-term sequelae of craniopharyngioma". Eur. J. Endocrinol. 176 (6): 755–767. doi:10.1530/EJE-17-0044. PMID 28325825. Vancouver style error: initials (help)
  2. Complications of Craniopharyngioma. National library of medicine. https://www.nlm.nih.gov/medlineplus/ency/article/000345.htm
  3. Complications. Cancer gov. http://www.cancer.gov/types/brain/hp/child-cranio-treatment-pdq#link/_40_toc
  4. Müller HL (June 2014). "Craniopharyngioma". Endocr. Rev. 35 (3): 513–43. doi:10.1210/er.2013-1115. PMID 24467716.
  5. Prognosis of Craniopharyngioma. Cancer gov. http://www.cancer.gov/types/brain/hp/child-cranio-treatment-pdq#link/_40_toc
  6. Prognosis. National Library of Medicine. https://www.nlm.nih.gov/medlineplus/ency/article/000345.htm
  7. Sofela, AA; Hettige, S; Curran, O; Bassi, S (Sep 2014). "Malignant transformation in craniopharyngiomas". Neurosurgery. 75 (3): 306–14, discussion 314. doi:10.1227/NEU.0000000000000380. PMID 24978859.


Template:WikiDoc Sources