Congenital syphilis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

The condition was well described in the 15th century and has long been recognized as a distinct syndrome in which the source is an infected adult. Several theories have been advanced to explain how the infection is transmitted, including transmission from a father infected with syphilis and transmission from an infant's nursing an infected wet nurse. Transplacental transmission from an asymptomatic infected mother was first described in 1906.