Congenital syphilis historical perspective: Difference between revisions

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*In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm or during delivery in the birth canal, or from infected milk or breasts.<ref name="Obladen2013">{{cite journal|last1=Obladen|first1=Michael|title=Curse on Two Generations: A History of Congenital Syphilis|journal=Neonatology|volume=103|issue=4|year=2013|pages=274–280|issn=1661-7819|doi=10.1159/000347107}}</ref>
*In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm or during delivery in the birth canal, or from infected milk or breasts.<ref name="Obladen2013">{{cite journal|last1=Obladen|first1=Michael|title=Curse on Two Generations: A History of Congenital Syphilis|journal=Neonatology|volume=103|issue=4|year=2013|pages=274–280|issn=1661-7819|doi=10.1159/000347107}}</ref>
*In 1905, Schaudinn and Hoffmann identified Spirochaeta  pallida.
*In 1905, Schaudinn and Hoffmann identified Spirochaeta  pallida.
*Transplacental transmission from an asymptomatic infected mother was first described in 1906.<ref name="urlGuidelines for the Prevention and Control of Congenital Syphilis">{{cite web |url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00026330.htm |title=Guidelines for the Prevention and Control of Congenital Syphilis |format= |work= |accessdate=}}</ref>
*[[Transplacental transmission]] from an asymptomatic infected mother was first described in 1906.<ref name="urlGuidelines for the Prevention and Control of Congenital Syphilis">{{cite web |url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00026330.htm |title=Guidelines for the Prevention and Control of Congenital Syphilis |format= |work= |accessdate=}}</ref>
*In 1943, Lentz and Ingraham reported penicillin as treatment for congenital syphilis.
*In 1943, Lentz and Ingraham reported [[penicillin]] as treatment for congenital syphilis.
*In 2006, the WHO launched a global effort to eliminate congenital syphilis.
*In 2006, the WHO launched a global effort to eliminate congenital syphilis.



Revision as of 13:38, 3 April 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Aravind Kuchkuntla, M.B.B.S[3]

Overview

Congenital syphilis was first described in an English 17th century in a pediatric textbook. Transplacental transmission from an asymptomatic infected mother was first described in 1906. Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis.

Historical Perspective

  • Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis. The condition was well described in the 15th century and has long been recognized as a syndrome transmitted from an infected adult.
  • In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm or during delivery in the birth canal, or from infected milk or breasts.[1]
  • In 1905, Schaudinn and Hoffmann identified Spirochaeta pallida.
  • Transplacental transmission from an asymptomatic infected mother was first described in 1906.[2]
  • In 1943, Lentz and Ingraham reported penicillin as treatment for congenital syphilis.
  • In 2006, the WHO launched a global effort to eliminate congenital syphilis.

References

  1. Obladen, Michael (2013). "Curse on Two Generations: A History of Congenital Syphilis". Neonatology. 103 (4): 274–280. doi:10.1159/000347107. ISSN 1661-7819.
  2. "Guidelines for the Prevention and Control of Congenital Syphilis".


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